Molecular Characteristics of Biliary Tract and Primary Liver Tumors

被引：8

作者：

Tsai, Susan ^{[1
]}

Gamblin, T. Clark ^{[1
]}

机构：

[1] Med Coll Wisconsin, Dept Surg, Div Surg Oncol, 8701 West Watertown Plank Rd, Milwaukee, WI 53226 USA

来源：

SURGICAL ONCOLOGY CLINICS OF NORTH AMERICA | 2019年 / 28卷 / 04期

关键词：

Intrahepatic cholangiocarcinoma; Hepatocellular carcinoma; Next-generation sequencing; Gene expression; Molecular subtype; HEPATOCELLULAR-CARCINOMA; SOMATIC MUTATIONS; GENE; FREQUENT; GROWTH; GENOME; PBRM1; ELF3;

D O I：

10.1016/j.soc.2019.06.004

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

With the recent decline in cost of high-throughput next-generation sequencing, detailed characterization of biliary tract and primary liver tumors continues to evolve. Recent studies have elucidated molecular signatures that reflect distinct pathways of carcinogenesis reflective of viral, parasitic, and toxin-related etiologic factors. With greater elucidation of the molecular pathogenesis of disease, novel targets that may be potential clinically actionable continue to be identified.

引用

页码：685 / +

页数：10

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