Self-rated walking pace and all-cause, cardiovascular disease and cancer mortality: individual participant pooled analysis of 50 225 walkers from 11 population British cohorts

被引:64
作者
Stamatakis, Emmanuel [1 ,2 ]
Kelly, Paul [3 ]
Strain, Tessa [3 ,4 ]
Murtagh, Elaine M. [5 ]
Ding, Ding [1 ,2 ]
Murphy, Marie H. [6 ]
机构
[1] Univ Sydney, Epidemiol Unit, Charles Perkins Ctr, Sydney, NSW, Australia
[2] Univ Sydney, Sch Publ Hlth, Fac Med & Hlth, Prevent Res Collaborat, Sydney, NSW, Australia
[3] Univ Edinburgh, Inst Sport Phys Educ & Hlth Sci, Phys Act Hlth Res Ctr, Edinburgh, Midlothian, Scotland
[4] Univ Cambridge, MRC, Epidemiol Unit, Cambridge, England
[5] Univ Limerick, Mary Immaculate Coll, Limerick, Ireland
[6] Univ Ulster, Sport & Exercise Sci Res Inst, Coleraine, Londonderry, North Ireland
基金
英国医学研究理事会;
关键词
walking; physical activity; epidemiology; public health; cohort study; PHYSICAL-ACTIVITY; HEALTH SURVEY; METAANALYSIS; ENGLAND; WOMEN; ASSOCIATION; PREVENTION; EXERCISE; PROFILE;
D O I
10.1136/bjsports-2017-098677
中图分类号
G8 [体育];
学科分类号
04 ; 0403 ;
摘要
Background/objectives Walking pace is associated with risk of premature mortality. However, whether this relationship is independent of total volume of physical activity and highest physical activity intensity remains unclear. We examined the associations between walking pace and cause-specific mortality, investigating the potential modifying effect of factors such as total physical activity volume, highest physical activity intensity, age, sex and body mass index (BMI). Methods Prospective pooled analysis of 11 population-based baseline surveys in England and Scotland between 1994 and2008 that were linked with mortality records. Multivariate-adjusted Cox proportional hazards models examined associations between walking pace (slow, average, brisk/fast) and all-cause, cancer and cardiovascular disease (CVD) mortality. Results 50225 walkers were entered in the core analyses. Among participants who did not experience an event in the first 2 years of follow-up (n=49731), walking at an average or brisk/fast pace was associated with a reduced risk of all-cause (20% (95% CI 12% to 28%) and 24% (95% CI 13% to 33%), respectively) and CVD mortality (24% (95% CI 9% to 36%) and 21% (95% CI 1% to 38%), respectively), compared with reporting walking at a slow pace. In stratified analyses, such associations were evident among those over 50 years, those not meeting the physical activity recommendations and those who did not undertake vigorous-intensity activity. There were no interactions by sex or BMI. No associations were seen between pace and cancer mortality. Conclusion Walking benefits health. Assuming causality, these analyses suggest that increasing walking pace could reduce risk for all-cause and CVD mortality. Walking pace could be emphasised in public health messages, especially in situations when increase in walking volume or frequency is less feasible.
引用
收藏
页码:761 / 768
页数:8
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