Stool bacterial load in preterm infants with necrotising enterocolitis

被引:13
作者
Abdulkadir, Bashir [1 ]
Nelson, Andrew [1 ]
Skeath, Tom [2 ]
Marrs, Emma C. L. [3 ]
Perry, John D. [3 ]
Cummings, Stephen P. [1 ]
Embleton, Nicholas D. [2 ]
Berrington, Janet E. [2 ]
Stewart, Christopher J. [1 ]
机构
[1] Northumbria Univ, Fac Hlth & Life Sci, Ellison Bldg, Newcastle Upon Tyne NE1 8ST, Tyne & Wear, England
[2] Royal Victoria Infirm, Newcastle Neonatal Serv, Newcastle Upon Tyne NE1 4LP, Tyne & Wear, England
[3] Freeman Rd Hosp, Dept Microbiol, Newcastle Upon Tyne NE7 7DN, Tyne & Wear, England
关键词
Preterm infant; Gut microbiome; Necrotising enterocolitis; qPCR;
D O I
10.1016/j.earlhumdev.2016.01.018
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Resected gut tissue in necrotising enterocolitis (NEC) has a higher bacterial load than controls. Quantitative PCR was performed on longitudinal NEC and control stool samples (n = 72). No significant difference in the total bacterial load was found between samples at diagnosis compared to controls or temporally within NEC. (C) 2016 Elsevier Ireland Ltd. All rights reserved.
引用
收藏
页码:1 / 2
页数:2
相关论文
共 5 条
[1]   The neonatal bowel microbiome in health and infection [J].
Berrington, Janet E. ;
Stewart, Christopher J. ;
Cummings, Stephen P. ;
Embleton, Nicholas D. .
CURRENT OPINION IN INFECTIOUS DISEASES, 2014, 27 (03) :236-243
[2]   Mucosa-Associated Bacterial Diversity in Necrotizing Enterocolitis [J].
Brower-Sinning, Rachel ;
Zhong, Diana ;
Good, Misty ;
Firek, Brian ;
Baker, Robyn ;
Sodhi, Chhinder P. ;
Hackam, David J. ;
Morowitz, Michael J. .
PLOS ONE, 2014, 9 (09)
[3]   Assessment of sample handling practices on microbial activity in sputum samples from patients with cystic fibrosis [J].
Nelson, A. ;
De Soyza, A. ;
Bourke, S. J. ;
Perry, J. D. ;
Cummings, S. P. .
LETTERS IN APPLIED MICROBIOLOGY, 2010, 51 (03) :272-277
[4]   Development of the human infant intestinal microbiota [J].
Palmer, Chana ;
Bik, Elisabeth M. ;
DiGiulio, Daniel B. ;
Relman, David A. ;
Brown, Patrick O. .
PLOS BIOLOGY, 2007, 5 (07) :1556-1573
[5]   Development of the Preterm Gut Microbiome in Twins at Risk of Necrotising Enterocolitis and Sepsis [J].
Stewart, Christopher J. ;
Marrs, Emma C. L. ;
Nelson, Andrew ;
Lanyon, Clare ;
Perry, John D. ;
Embleton, Nicholas D. ;
Cummings, Stephen P. ;
Berrington, Janet E. .
PLOS ONE, 2013, 8 (08)