Cu-catalyzed tandem C-N bond formation for the synthesis of pyrroles and heteroarylpyrroles

被引：134
|
作者：
Martin, Ruben [1 ]
Larsen, Catharine H. [1 ]
Cuenca, Ana [1 ]
Buchwald, Stephen L. [1 ]
机构：
[1] MIT, Dept Chem, Cambridge, MA 02139 USA
来源：
ORGANIC LETTERS | 2007年 / 9卷 / 17期
关键词：
D O I：
10.1021/ol7014225
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A highly efficient Cu-catalyzed tandem C-N bond-forming reaction of 1,4-dihalo-1,3-dienes has been developed. The transformation allows the synthesis of pyrroles and heteroarylpyrroles with a wide variety of functional groups and substitution patterns from readily available precursors.
引用
收藏
页码：3379 / 3382
页数：4
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