Experimental bacteriophage protection against Staphylococcus aureus abscesses in a rabbit model

被引：139

作者：

Wills, QF ^{[1
]}

Kerrigan, C ^{[1
]}

Soothill, JS ^{[1
]}

机构：

[1] UCL, Inst Child Hlth, Infect Dis & Microbiol Unit, London, England

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2005年 / 49卷 / 03期

关键词：

D O I：

10.1128/AAC.49.3.1220-1221.2005

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

In a rabbit model of wound infection caused by Staphylococcus aureus, 2 x 10(9) PFU of staphylococcal phage prevented abscess formation in rabbits when it was injected simultaneously with S. aureus (8 x 10(7) CFU) into the same subcutaneous site. Phage multiplied in the tissues. Phages might be a valuable prophylaxis against staphylococcal infection.

引用

页码：1220 / 1221

页数：2

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