Motor block during patient-controlled epidural analgesia with ropivacaine or ropivacaine/fentanyl after intrathecal bupivacaine for Caesarean section

被引:16
作者
Buggy, DJ
Hall, NA
Shah, J
Brown, J
Williams, J
机构
[1] Univ Leicester, Leicester Gen Hosp, Dept Obstet Anaesthesia, Leicester LE5 4PW, Leics, England
[2] Univ Leicester, Dept Anaesthesia & Pain Management, Leicester LE5 4PW, Leics, England
关键词
anaesthetic techniques; epidural; analgesia; patient-controlled; anaesthetics; local; ropivacaine; analgesics; opioid; anaesthesia; obstetrics;
D O I
10.1093/bja/85.3.468
中图分类号
R614 [麻醉学];
学科分类号
100217 ;
摘要
We compared patient-controlled epidural analgesia (PCEA) with ropivacaine alone or combined with fentanyl in terms of analgesic efficacy, motor weakness and side-effects in patients who had received spinal anaesthesia for elective Caesarean section. ASA 1 patients received combined spinal-epidural anaesthesia and were randomly assigned, in a double-blind study, into two groups after operation: group R (n = 23) received PCEA ropivacaine 0.1%, bolus 5 mg, lockout 15 min, 3 mg h(-1) background infusion, and group RF (n = 24) received PCEA 0.1% ropivacaine/fentanyl 2 mu g ml(-1) at identical settings. Pain and satisfaction on a 100 mm visual analogue scale (VAS) and side-effects were noted. Incidence of motor weakness (Bromage grade 1 or higher) was 48% (11/23) at 8 h in group R compared with 13% (3/24) in group RF (P = 0.025). Pain scores on movement were lower in group RF at 8 and 12 h and at rest at 6 and 8 h (P < 0.05 for each comparison). Analgesic consumption was less in RF (P = 0.041), but there was no difference in time to first request for supplementary analgesia. Patient satisfaction with postoperative analgesia (mean (SD)) was higher in RF (79 (23) vs 57 (29) mm, P = 0.045). Caution should be exercised using ropivacaine PCEA after spinal bupivacaine for Caesarean section, because its reputed motor-sparing property may be unreliable.
引用
收藏
页码:468 / 470
页数:3
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