An effective sporicidal reagent against Bacillus subtilis spores

被引：16
作者：
Kida, N
Mochizuki, Y
Taguchi, F
机构：
[1] Minist Hlth Labour & Welf, Niigata Quarantine Stn, Niigata 9500072, Japan
[2] Kitasato Univ, Dept Clin Microbiol, Sch Allied Hlth Sci, Kanagawa 2288555, Japan
来源：
MICROBIOLOGY AND IMMUNOLOGY | 2003年 / 47卷 / 04期
关键词：
sporicidal reagent; ethanol; EDTA; ferric chloride;
D O I：
10.1111/j.1348-0421.2003.tb03396.x
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
We developed a reagent which showed significant sporicidal activity against Bacillus subtilis spores. This reagent was composed of ethylenediaminetetraacetic acid, disodium salt (EDTA-2Na), ferric chloride hexahydrate (FeCl3 . 6H(2)O) and ethanol (tentatively designated as the ethanol reagent). The ethanol reagent showed pH- and temperature-dependent sporicidal activity. At pH 0.3, its activity was almost the same as that of 0.05% sodium hypochlorite at 20 C and was higher at 37 C than at 20 C. The activity of the ethanol reagent was similar both with and without 10% serum. The ethanol reagent might be applicable for disinfecting Bacillus spores.
引用
收藏
页码：279 / 283
页数：5
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