Synthesis of 4-(pyrazol-5-yl)-1,2,4-triazole-3-thiones

被引：28

作者：

Vicentini, CB ^{[1
]}

Manfrini, M ^{[1
]}

Veronese, AC ^{[1
]}

Guarneri, M ^{[1
]}

机构：

[1] Univ Ferrara, Dipartimento Sci Farmaceut, I-44100 Ferrara, Italy

来源：

JOURNAL OF HETEROCYCLIC CHEMISTRY | 1998年 / 35卷 / 01期

关键词：

D O I：

10.1002/jhet.5570350106

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Condensation of pyrazolyl isothiocyanates 2 with N-substituted hydrazines provided the 2-methyl/phenyl-4-(pyrazol-5-yl)thiosemicarbazides 3. Cyclization of 3 with formic acid-acetic anhydride or with triethyl orthoacetate-acetic anhydride provided 4-(pyrazol-5-yl)-1,2,4-triazole-3-thiones 4a-f and 5-methyl-4-(pyrazol-5-yl)-1,2,4-triazole-3-thiones 4g-1 respectively.

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页码：29 / 32

页数：4

相关论文

共 25 条

[1]

GIORI P, 1985, FARMACO-ED SCI, V40, P795

[2] SYNTHESIS OF 4-THIOCARBAMOYL-5-AMINOPYRAZOLES [J].

GIORI, P ;

VERONESE, AC ;

VICENTINI, CB ;

GUARNERI, M .

JOURNAL OF HETEROCYCLIC CHEMISTRY, 1985, 22 (04) :1093-1096

[3]

GUARNERI M, 1968, GAZZ CHIM ITAL, V98, P568

[4]

MICHAELIS A, 1905, LIEBIGS ANN CHEM, V339, P138

[5] SYNTHESIS AND INVITRO ANTIFUNGAL ACTIVITY OF 6-TRIFLUOROMETHYLPYRAZOLO[3,4-D]PYRIMIDINES [J].

POLI, T ;

VICENTINI, CB ;

BRANDOLINI, V ;

VERONESE, AC ;

MANFRINI, M ;

GUARNERI, M ;

GIORI, P .

PESTICIDE SCIENCE, 1989, 25 (02) :161-169

[6] SYNTHESIS AND ACTIVITY OPTIMIZATION OF HERBICIDAL SUBSTITUTED 4-ARYL-1,2,4-TRIAZOLE-5(1H)-THIONES [J].

SIMMONS, KA ;

DIXSON, JA ;

HALLING, BP ;

PLUMMER, EL ;

PLUMMER, MJ ;

TYMONKO, JM ;

SCHMIDT, RJ ;

WYLE, MJ ;

WEBSTER, CA ;

BAVER, WA ;

WITKOWSKI, DA ;

PETERS, GR ;

GRAVELLE, WD .

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 1992, 40 (02) :297-305

[7] THE REACTION OF MALONONITRILE WITH SUBSTITUTED HYDRAZINES - NEW ROUTES TO 4-AMINOPYRAZOLO[3,4-D]PYRIMIDINES [J].

TAYLOR, EC ;

HARTKE, KS .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1959, 81 (10) :2456-2464

[8]

TOMLIN C, 1994, PESTICIDE MANUAL, P873

[9] A NEW FUSED HETEROCYCLIC SYSTEM - 6H-PYRAZOLO[3,4-C][1,2,5]THIADIAZINE 2,2-DIOXIDE [J].

VICENTINI, CB ;

VERONESE, AC ;

POLI, T ;

GUARNERI, M ;

GIORI, P ;

FERRETTI, V .

JOURNAL OF HETEROCYCLIC CHEMISTRY, 1989, 26 (03) :797-803

[10]

Vicentini CB, 1996, FARMACO, V51, P609