Group-based cognitive behavioural psychotherapy for children and adolescents with ASD: the randomized, multicentre, controlled SOSTA - net trial

被引:43
作者
Freitag, Christine M. [1 ]
Jensen, Katrin [2 ]
Elsuni, Leyla [1 ]
Sachse, Michael [1 ]
Herpertz-Dahlmann, Beate [3 ]
Schulte-Ruether, Martin [3 ]
Haenig, Susann [4 ]
von Gontard, Alexander [4 ]
Poustka, Luise [5 ,6 ]
Schad-Hansjosten, Tanja [5 ]
Wenzl, Christina [7 ]
Sinzig, Judith [7 ,8 ]
Taurines, Regina [9 ]
Geissler, Julia [9 ]
Kieser, Meinhard [2 ]
Cholemkery, Hannah [1 ]
机构
[1] Goethe Univ Frankfurt, Univ Hosp, Dept Child & Adolescent Psychiat, Psychosomat & Psychotherapy, D-60528 Frankfurt, Germany
[2] Heidelberg Univ, Inst Med Biometry & Informat, Heidelberg, Germany
[3] Univ Hosp RWTH Aachen, Dept Child & Adolescent Psychiat, Psychosomat & Psychotherapy, Aachen, Germany
[4] Univ Saarland, Hosp Homburg, Dept Child & Adolescent Psychiat, Psychosomat & Psychotherapy, D-66123 Saarbrucken, Germany
[5] Heidelberg Univ, Dept Child & Adolescent Psychiat & Psychotherapy, Cent Inst Mental Hlth, Med Fac Mannheim, Heidelberg, Germany
[6] Med Univ Vienna, Dept Child & Adolescent Psychiat, Vienna, Austria
[7] Univ Hosp Koln, Dept Child & Adolescent Psychiat, Psychosomat & Psychotherapy, Cologne, Germany
[8] LVR Klin Bonn, Dept Child & Adolescent Psychiat, Bonn, Germany
[9] Univ Hosp Wurzburg, Dept Child & Adolescent Psychiat, Psychosomat & Psychotherapy, Wurzburg, Germany
关键词
Group therapy; social skills; autism spectrum disorders; randomized-controlled trial; HIGH-FUNCTIONING AUTISM; SOCIAL-SKILLS; SPECTRUM DISORDER; DIFFICULTIES QUESTIONNAIRE; EMOTION RECOGNITION; ASPERGER-SYNDROME; YOUNG-CHILDREN; INTERVENTION; POPULATION; ADULTHOOD;
D O I
10.1111/jcpp.12509
中图分类号
B844 [发展心理学(人类心理学)];
学科分类号
040202 ;
摘要
Background: Group-based psychotherapy in Autism Spectrum Disorder (ASD) has predominantly been studied in the United States by small studies in school-aged children without long-term follow-up. We report results of a large, confirmatory, multicentre randomized-controlled phase-III trial in children and adolescents studying the ASD specific, manualized group-based cognitive behavioural SOSTA-FRA approach. Methods: High-functioning ASD individuals aged 8-19 years old were randomized to 12 sessions SOSTA-FRA or treatment as usual. Primary outcomes were change in total raw score of the parent-rated Social Responsiveness Scale (pSRS) between baseline (T2) and end of intervention (T4), and between T2 and 3 months after end of intervention (T5). Trial registration: ISRCTN94863788. Results: Between 20/5/2010 and 14/2/2013, n = 320 ASD patients were screened, n = 228 patients were randomized, and N = 209 analysed. Mean pSRS difference between groups at T4 was -6.5 (95% CI -11.6 to -1.4; p = .013), and at T5 -6.4 (-11.5 to -1.3, p = .015). Pre-treatment SRS and IQ were positively associated with stronger improvement at T4 and T5. Conclusions: Short-term ASD-specific add-on group-based psychotherapy has shown postintervention efficacy with regard to parent-rated social responsiveness predominantly in male high-functioning children and adolescents with ASD. Future studies should implement blinded standardized observational measures of peer-related social interaction.
引用
收藏
页码:596 / 605
页数:10
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