Viewpoint: The prothrombotic state in heart failure: A maladaptive inflammatory response?

被引：33

作者：

Chong, Aun-Yeong ^{[1
]}

Lip, Gregory Y. H. ^{[1
]}

机构：

[1] Univ Birmingham, Haemostasis Thrombosis & Vasc Biol Unit, Dept Med, City Hosp, Birmingham B18 7QH, W Midlands, England

来源：

EUROPEAN JOURNAL OF HEART FAILURE | 2007年 / 9卷 / 02期

关键词：

prothrombotic state; inflammation; heart failure;

D O I：

10.1016/j.ejheart.2006.05.009

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Patients with heart failure (HF) are at an increased risk of stroke, sudden death and venous thromboembolism, which are all linked to thrombus formation (thrombogenesis). The present 'viewpoint' article will discuss how the prothrombotic state in HF may be perpetuated by a chronic inflammatory state that is maladaptive. Indeed, there is considerable evidence that thrombogenesis and endothelial (dys)function can be intimately linked to inflammation in HF. (c) 2006 European Society of Cardiology. Published by Elsevier B.V. All rights reserved.

引用

页码：124 / 128

页数：5

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