In order to realize the health run smoothly for modern hospital, it must strengthen the maintenance of medical equipment management. The degree of precision instrument reflected the hospital diagnosis and treatment level and ability. Through the study of the modernization of hospital medical equipment maintenance management, this study achieve the goal of construction of modern hospital. The normal operation of the large medical equipment ensured the normal operation of the hospital work. This article mainly expounded the present situation of comprehensive hospital medical equipment maintenance management, the footprints were put forward based on the present situation of hospital medical equipment maintenance management measures to modernize.