Long-term side effects of glucocorticoids

被引：637

作者：

Oray, Merih ^{[1
,2
,3
]}

Abu Samra, Khawla ^{[1
,2
]}

Ebrahimiadib, Nazanin ^{[1
,2
]}

Meese, Halea ^{[1
,2
]}

Foster, C. Stephen ^{[1
,2
,4
]}

机构：

[1] Massachusetts Eye Res & Surg Inst, 1440 Main St, Waltham, MA 02142 USA

[2] Ocular Immunol & Uveitis Fdn, Waltham, MA USA

[3] Istanbul Univ, Istanbul Fac Med, Dept Ophthalmol, Istanbul, Turkey

[4] Harvard Univ, Sch Med, Dept Ophthalmol, Boston, MA USA

来源：

EXPERT OPINION ON DRUG SAFETY | 2016年 / 15卷 / 04期

关键词：

glucocorticoids; immunosuppression; side effects; corticosteroids; RHEUMATOID-ARTHRITIS; INDUCED OSTEOPOROSIS; ADVERSE EVENTS; RECEPTOR AGONISTS; PEPTIC-ULCER; RISK-FACTORS; CORTICOSTEROIDS; THERAPY; COMPLICATIONS; DISEASE;

D O I：

10.1517/14740338.2016.1140743

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Introduction: Glucocorticoids represent the standard therapy for reducing inflammation and immune activation in various diseases. However, as with any potent medication, they are not without side effects. Glucocorticoid-associated side effects may involve most major organ systems. Musculoskeletal, gastrointestinal, cardiovascular, endocrine, neuropsychiatric, dermatologic, ocular, and immunologic side effects are all possible.Areas Covered: This article analyzes English-language literature and provides an update on the most recent literature regarding side effects of systemic glucocorticoid treatment.Expert Opinion: The risk/benefit ratio of glucocorticoid therapy can be improved by proper use. Careful monitoring and using appropriate preventive strategies can potentially minimize side effects.

引用

页码：457 / 465

页数：9

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