Physical activity, obesity and survival in diffuse large B-cell and follicular lymphoma cases

被引：22
作者：
Boyle, Terry [1 ,2 ]
Connors, Joseph M. [3 ]
Gascoyne, Randy D. [3 ]
Berry, Brian R. [4 ]
Sehn, Laurie H. [3 ]
Bashash, Morteza [5 ]
Spinelli, John J. [6 ,7 ]
机构：
[1] Curtin Univ, Sch Publ Hlth, Perth, WA, Australia
[2] British Columbia Canc Agcy, Canc Control Res, Vancouver, BC, Canada
[3] British Columbia Canc Agcy, Ctr Lymphoid Canc, Vancouver, BC, Canada
[4] Royal Jubilee Hosp, Dept Pathol & Lab Med, Victoria, BC, Canada
[5] Univ Toronto, Dalla Lana Sch Publ Hlth, Toronto, ON, Canada
[6] British Columbia Canc Agcy, Populat Oncol, Vancouver, BC, Canada
[7] Univ British Columbia, Sch Populat & Publ Hlth, Vancouver, BC, Canada
来源：
BRITISH JOURNAL OF HAEMATOLOGY | 2017年 / 178卷 / 03期
基金：
英国医学研究理事会; 加拿大健康研究院;
关键词：
body mass index; diffuse large B-cell lymphoma; follicular lymphoma; physical activity; prognosis; NON-HODGKIN-LYMPHOMA; BODY-MASS INDEX; RISK; CANCER;
D O I：
10.1111/bjh.14702
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
There is limited information concerning the impact of physical activity and obesity on non-Hodgkin lymphoma (NHL) prognosis. We examined the associations between pre-diagnosis physical activity and body mass index (BMI) with survival in 238 diffuse large B-cell (DLBCL) and 175 follicular lymphoma cases, with follow-up from 2000 to 2015. The most physically active DLBCL cases had 41% lower risk of dying in the follow-up period than the least active [Hazard ratio (HR) = 0.59, 95% confidence interval (CI) = 0.36-0.96], while obese follicular lymphoma cases had a 2.5-fold risk of dying (HR = 2.52, 95% CI = 1.27-5.00) compared with cases with normal BMI. NHL-specific survival results were similar.
引用
收藏
页码：442 / 447
页数：6
相关论文
共 14 条
  • [1] [Anonymous], 2015, CANC FACTS FIG 2015
  • [2] Australian Institute of Health and Welfare, 2015, AUSTR I HLTH WELF CA, V90
  • [3] Lifetime Physical Activity and the Risk of Non-Hodgkin Lymphoma
    Boyle, Terry
    Gallagher, Richard P.
    Gascoyne, Randy D.
    Connors, Joseph M.
    Le, Nhu D.
    Spinelli, John J.
    [J]. CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION, 2015, 24 (05) : 873 - 877
  • [4] Effects of supervised exercise on progression-free survival in lymphoma patients: an exploratory follow-up of the HELP Trial
    Courneya, Kerry S.
    Friedenreich, Christine M.
    Franco-Villalobos, Conrado
    Crawford, Jennifer J.
    Chua, Neil
    Basi, Sanraj
    Norris, Mary K.
    Reiman, Tony
    [J]. CANCER CAUSES & CONTROL, 2015, 26 (02) : 269 - 276
  • [5] The Role of Obesity in Cancer Survival and Recurrence
    Demark-Wahnefried, Wendy
    Platz, Elizabeth A.
    Ligibel, Jennifer A.
    Blair, Cindy K.
    Courneya, Kerry S.
    Meyerhardt, Jeffrey A.
    Ganz, Patricia A.
    Rock, Cheryl L.
    Schmitz, Kathryn H.
    Wadden, Thomas
    Philip, Errol J.
    Wolfe, Bruce
    Gapstur, Susan M.
    Ballard-Barbash, Rachel
    McTiernan, Anne
    Minasian, Lori
    Nebeling, Linda
    Goodwin, Pamela J.
    [J]. CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION, 2012, 21 (08) : 1244 - 1259
  • [6] Physical Activity and Cancer Outcomes: A Precision Medicine Approach
    Friedenreich, Christine M.
    Neilson, Heather K.
    Farris, Megan S.
    Courneya, Kerry S.
    [J]. CLINICAL CANCER RESEARCH, 2016, 22 (19) : 4766 - 4775
  • [7] Physical Activity in Relation to Risk of Hematologic Cancers: A Systematic Review and Meta-analysis
    Jochem, Carmen
    Leitzmann, Michael F.
    Keimling, Marlen
    Schmid, Daniela
    Behrens, Gundula
    [J]. CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION, 2014, 23 (05) : 833 - 846
  • [8] Chemotherapy dosing in overweight and obese patients with cancer
    Lyman, Gary H.
    Sparreboom, Alex
    [J]. NATURE REVIEWS CLINICAL ONCOLOGY, 2013, 10 (08) : 451 - 459
  • [9] Body mass index and other anthropometric parameters in patients with diffuse large B-cell lymphoma: physiopathological significance and predictive value in the immunochemotherapy era
    Sarkozy, Clementine
    Camus, Vincent
    Tilly, Herve
    Salles, Gilles
    Jardin, Fabrice
    [J]. LEUKEMIA & LYMPHOMA, 2015, 56 (07) : 1959 - 1968
  • [10] A PREDICTIVE MODEL FOR AGGRESSIVE NON-HODGKINS-LYMPHOMA
    SHIPP, MA
    HARRINGTON, DP
    ANDERSON, JR
    ARMITAGE, JO
    BONADONNA, G
    BRITTINGER, G
    CABANILLAS, F
    CANELLOS, GP
    COIFFIER, B
    CONNORS, JM
    COWAN, RA
    CROWTHER, D
    DAHLBERG, S
    ENGELHARD, M
    FISHER, RI
    GISSELBRECHT, C
    HORNING, SJ
    LEPAGE, E
    LISTER, TA
    MEERWALDT, JH
    MONTSERRAT, E
    NISSEN, NI
    OKEN, MM
    PETERSON, BA
    TONDINI, C
    VELASQUEZ, WA
    YEAP, BY
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 1993, 329 (14) : 987 - 994
12