Physical activity, obesity and survival in diffuse large B-cell and follicular lymphoma cases

被引：22

作者：

Boyle, Terry ^{[1
,2
]}

Connors, Joseph M. ^{[3
]}

Gascoyne, Randy D. ^{[3
]}

Berry, Brian R. ^{[4
]}

Sehn, Laurie H. ^{[3
]}

Bashash, Morteza ^{[5
]}

Spinelli, John J. ^{[6
,7
]}

机构：

[1] Curtin Univ, Sch Publ Hlth, Perth, WA, Australia

[2] British Columbia Canc Agcy, Canc Control Res, Vancouver, BC, Canada

[3] British Columbia Canc Agcy, Ctr Lymphoid Canc, Vancouver, BC, Canada

[4] Royal Jubilee Hosp, Dept Pathol & Lab Med, Victoria, BC, Canada

[5] Univ Toronto, Dalla Lana Sch Publ Hlth, Toronto, ON, Canada

[6] British Columbia Canc Agcy, Populat Oncol, Vancouver, BC, Canada

[7] Univ British Columbia, Sch Populat & Publ Hlth, Vancouver, BC, Canada

来源：

BRITISH JOURNAL OF HAEMATOLOGY | 2017年 / 178卷 / 03期

基金：

英国医学研究理事会; 加拿大健康研究院;

关键词：

body mass index; diffuse large B-cell lymphoma; follicular lymphoma; physical activity; prognosis; NON-HODGKIN-LYMPHOMA; BODY-MASS INDEX; RISK; CANCER;

D O I：

10.1111/bjh.14702

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

There is limited information concerning the impact of physical activity and obesity on non-Hodgkin lymphoma (NHL) prognosis. We examined the associations between pre-diagnosis physical activity and body mass index (BMI) with survival in 238 diffuse large B-cell (DLBCL) and 175 follicular lymphoma cases, with follow-up from 2000 to 2015. The most physically active DLBCL cases had 41% lower risk of dying in the follow-up period than the least active [Hazard ratio (HR) = 0.59, 95% confidence interval (CI) = 0.36-0.96], while obese follicular lymphoma cases had a 2.5-fold risk of dying (HR = 2.52, 95% CI = 1.27-5.00) compared with cases with normal BMI. NHL-specific survival results were similar.

引用

页码：442 / 447

页数：6

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