The influence of vitamins E and C and exercise on brain aging

被引：14
作者：
Mock, J. Thomas [1 ]
Chaudhari, Kiran [1 ]
Sidhu, Akram [1 ]
Sumien, Nathalie [1 ]
机构：
[1] Univ North Texas Hlth Sci Ctr Ft Worth, Inst Hlth Aging, Ctr Neurosci Discovery, Ft Worth, TX 76107 USA
来源：
EXPERIMENTAL GERONTOLOGY | 2017年 / 94卷
基金：
美国国家卫生研究院;
关键词：
Exercise; Antioxidants; Brain function; Vitamin E; Vitamin C; Aging; Cognition; Motor function; ADULT HIPPOCAMPAL NEUROGENESIS; OXIDATIVE STRESS; COGNITIVE FUNCTION; PHYSICAL-EXERCISE; PROTEIN OXIDATION; ALPHA-TOCOPHEROL; RESISTANCE EXERCISE; MODERATE EXERCISE; COENZYME Q(10); CALORIC-INTAKE;
D O I：
10.1016/j.exger.2016.12.008
中图分类号：
R592 [老年病学]; C [社会科学总论];
学科分类号：
03 ; 0303 ; 100203 ;
摘要：
Age-related declines in motor and cognitive function have been associated with increases in oxidative stress. Accordingly, interventions capable of reducing the oxidative burden would be capable of preventing or reducing functional declines occurring during aging. Popular interventions such as antioxidant intake and moderate exercise are often recommended to attain healthy aging and have the capacity to alter redox burden. This review is intended to summarize the outcomes of antioxidant supplementation (more specifically of vitamins C and E) and exercise training on motor and cognitive declines during aging, and on measures of oxidative stress. Additionally, we will address whether co-implementation of these two types of interventions can potentially further their individual benefits. Together, these studies highlight the importance of using translationally-relevant parameters for interventions and to study their combined outcomes on healthy brain aging. (C) 2016 Elsevier Inc. All rights reserved.
引用
收藏
页码：69 / 72
页数：4
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