HEMATOLOGY Trials and tribulations in primary CNS lymphoma

被引：6

作者：

Ansell, Stephen M. ^{[1
]}

Rajkumar, S. Vincent ^{[1
]}

机构：

[1] Mayo Clin, Div Hematol, Rochester, MN 55905 USA

来源：

NATURE REVIEWS CLINICAL ONCOLOGY | 2010年 / 7卷 / 03期

关键词：

NON-HODGKIN-LYMPHOMA; METHOTREXATE; RADIOTHERAPY; THERAPY; BRAIN; CHEMOTHERAPY; SURVIVAL; RTOG;

D O I：

10.1038/nrclinonc.2010.9

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

A minority of patients with primary central nervous system lymphoma (PCNSL) achieve a complete response to therapy and most patients have a poor prognosis. A recent randomized phase II trial demonstrated that the addition of high-dose cytarabine to high-dose methotrexate increases the complete response rate and improves patient outcome.

引用

页码：125 / 126

页数：2

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