Drug-Induced Liver Injury After COVID-19 Vaccine

被引：39

作者：

Mann, Rupinder ^{[1
]}

Sekhon, Sommer ^{[2
]}

Sekhon, Sandeep ^{[3
]}

机构：

[1] St Agnes Med Ctr, Internal Med, Fresno, CA 93720 USA

[2] Clovis North High Sch, Biol, Fresno, CA USA

[3] St Agnes Med Ctr, Gastroenterol & Hepatol, Fresno, CA USA

来源：

CUREUS JOURNAL OF MEDICAL SCIENCE | 2021年 / 13卷 / 07期

关键词：

covid-19; vaccine; liver dysfunctions; pandemic; drug-induced liver injury; AUTOIMMUNE HEPATITIS; POPULATION; DIAGNOSIS;

D O I：

10.7759/cureus.16491

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The first case of coronavirus disease 2019 (COVID-19) was reported in December 2019 in China. World Health Organization declared it a pandemic on March 11, 2020. It has caused significant morbidity and mortality worldwide. Persistent symptoms and serious complications are being reported in patients who survived COVID-19 infection, but long-term sequelae are still unknown. Several vaccines against COVID-19 have been approved for emergency use around the globe. These vaccines have excellent safety profiles with few reported side effects. Drug-induced hepatotoxicity is mainly seen with different drugs or chemicals. There are only a few reported cases of hepatotoxicity with vaccines. We present a case of liver injury after administration of the vaccine against the COVID-19 infection.

引用

页数：5

共 29 条

[1]

[Anonymous], 2021, WHO CORONAVIRUS DIS

[2] Efficacy and Safety of the mRNA-1273 SARS-CoV-2 Vaccine [J].

Baden, Lindsey R. ;

El Sahly, Hana M. ;

Essink, Brandon ;

Kotloff, Karen ;

Frey, Sharon ;

Novak, Rick ;

Diemert, David ;

Spector, Stephen A. ;

Rouphael, Nadine ;

Creech, C. Buddy ;

McGettigan, John ;

Khetan, Shishir ;

Segall, Nathan ;

Solis, Joel ;

Brosz, Adam ;

Fierro, Carlos ;

Schwartz, Howard ;

Neuzil, Kathleen ;

Corey, Larry ;

Gilbert, Peter ;

Janes, Holly ;

Follmann, Dean ;

Marovich, Mary ;

Mascola, John ;

Polakowski, Laura ;

Ledgerwood, Julie ;

Graham, Barney S. ;

Bennett, Hamilton ;

Pajon, Rolando ;

Knightly, Conor ;

Leav, Brett ;

Deng, Weiping ;

Zhou, Honghong ;

Han, Shu ;

Ivarsson, Melanie ;

Miller, Jacqueline ;

Zaks, Tal .

NEW ENGLAND JOURNAL OF MEDICINE, 2021, 384 (05) :403-416

[3] Hepatitis A vaccine associated with autoimmune hepatitis [J].

Berry, P. A. ;

Smith-Laing, G. .

WORLD JOURNAL OF GASTROENTEROLOGY, 2007, 13 (15) :2238-2239

[4] Incidence, Presentation, and Outcomes in Patients With Drug-Induced Liver Injury in the General Population of Iceland [J].

Bjornsson, Einar S. ;

Bergmann, Ottar M. ;

Bjornsson, Helgi K. ;

Kvaran, Runar B. ;

Olafsson, Sigurdur .

GASTROENTEROLOGY, 2013, 144 (07) :1419-U168

[5] EASL position paper on the use of COVID-19 vaccines in patients with chronic liver diseases, hepatobiliary cancer and liver transplant recipients [J].

Cornberg, Markus ;

Buti, Maria ;

Eberhardt, Christiane S. ;

Grossi, Paolo Antonio ;

Shouval, Daniel .

JOURNAL OF HEPATOLOGY, 2021, 74 (04) :944-951

[6] Acute exacerbation of autoimmune hepatitis induced by Twinrix [J].

Csepregi, Antal ;

Treiber, Gerhard ;

Roecken, Christoph ;

Malfertheiner, Peter .

WORLD JOURNAL OF GASTROENTEROLOGY, 2005, 11 (26) :4114-4116

[7] Drug-Induced Liver Injury [J].

Fisher, Kurt ;

Vuppalanchi, Raj ;

Saxena, Romil .

ARCHIVES OF PATHOLOGY & LABORATORY MEDICINE, 2015, 139 (07) :876-887

[8]

Fix OK, 2021, HEPATOLOGY, V74, P1049, DOI [10.1002/hep.31751/suppinfo, 10.1002/hep.31751]

[9]

Frider Bernardo, 2013, Case Reports Hepatol, V2013, P406901, DOI 10.1155/2013/406901

[10] Idiosyncratic drug hepatotoxicity [J].

Kaplowitz, N .

NATURE REVIEWS DRUG DISCOVERY, 2005, 4 (06) :489-499

← 1 2 3 →