pH-Sensitive Water-Soluble Nanospheric Imprinted Hydrogels Prepared as Horseradish Peroxidase Mimetic Enzymes

被引：134

作者：

Chen, Zhiyong ^{[1
]}

Xu, Li ^{[1
]}

Liang, Yuan ^{[1
]}

Zhao, Meiping ^{[1
]}

机构：

[1] Peking Univ, Coll Chem & Mol Engn, Key Lab Bioorgan Chem & Mol Engn, Beijing Natl Lab Mol Sci,Minist Educ, Beijing 100871, Peoples R China

来源：

ADVANCED MATERIALS | 2010年 / 22卷 / 13期

基金：

中国国家自然科学基金;

关键词：

MOLECULAR RECOGNITION; AQUEOUS CONDITIONS; CATALYTIC-ACTIVITY; HOMOVANILLIC-ACID; POLYMERS; MICROGELS; NANOGELS; SUBSTRATE; OXIDATION; GELS;

D O I：

10.1002/adma.200903122

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Water-soluble hydrogel nanoparticles have been synthesized by the incorporation of the stimuli-sensitive monomer of N-isopropylacrylamide (NIPAM) to a catalytic, molecularly imprinted system. The unique properties of pNIPAM copolymerized with cationic and anionic polymers offers a homogenously biocompatible catalytic system with switchable response to pH change. The maximum catalytic efficiency can thus be significantly increased.

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收藏

页码：1488 / +

页数：6

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