First-in-human (FIH) trial evaluating immune activation and safety of PIN-2 administered intravenously to patients with advanced solid tumors.

被引：0

作者：

Bier, Colin

Millward, Michael

Kotasek, Dusan

Gorelick, Kenneth J.

Goldberg, Joshua Brian

机构：

[1] PIN Pharma Inc, New York, NY USA

[2] Sch Med & Pharmacol, Nedlands, WA, Australia

[3] Adelaide Canc Ctr, Kurralta Pk, Adelaide, SA, Australia

[4] Univ Adelaide, Kurralta Pk, Adelaide, SA, Australia

来源：

JOURNAL OF CLINICAL ONCOLOGY | 2019年 / 37卷 / 15期

关键词：

D O I：

10.1200/JCO.2019.37.15_suppl.2600

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

2600

引用

页数：1

共 50 条

[41] First-in-human (FIH) phase I data of HST-1011, an oral CBL-B inhibitor, in patients with advanced solid tumors [J].

Sanborn, R. E. ;

Patel, M. R. ;

Rodon, J. ;

Thein, K. Z. ;

Friedman, C. ;

Levitz, D. ;

Ngirailemesang, I. ;

Goodman, A. ;

Agarwal, P. ;

Friedman, E. ;

Danaee, H. ;

Robell, K. ;

Jaeger, S. ;

Sun, H. ;

Debanne, E. ;

Dunn, J. ;

Wright, E. ;

Reilly, T. ;

Luke, J. J. ;

Redig, A. .

ANNALS OF ONCOLOGY, 2024, 35 :S675-S676

[42] First-in-human trial of the oral ataxia telangiectasia and Rad3-related (ATR) inhibitor BAY 1895344 in patients (pts) with advanced solid tumors. [J].

De Bono, Johann S. ;

Tan, David Shao Peng ;

Caldwell, Reece ;

Terbuch, Angelika ;

Goh, Boon C. ;

Heong, Valerie ;

Haris, Noor Md ;

Bashir, Saira ;

Hong, David S. ;

Meric-Bernstam, Funda ;

Bordia, Sonal ;

Liu, Li ;

Wilkinson, Gary ;

Hreiki, Joseph ;

Wengner, Antje ;

Fischer, Kerstin ;

Boix, Oliver ;

Lagkadinou, Eleni ;

Plummer, Elizabeth ;

Yap, Timothy A. .

JOURNAL OF CLINICAL ONCOLOGY, 2019, 37 (15)

[43] First-in-class, first-in-human phase I trial of KPT-330, a selective inhibitor of nuclear export (SINE) in patients (pts) with advanced solid tumors. [J].

Razak, Albiruni R. A. ;

Soerensen, Morten Mau ;

Mahipal, Amit ;

Shacham, Sharon ;

Yau, Cindy Y. F. ;

Lassen, Ulrik Niels ;

McCauley, Dilara ;

Cooksey, Jennifer ;

Tan, David Shao Peng ;

Saint-Martin, Jean-Richard ;

Landesman, Yossi ;

Pond, Gregory ;

Oza, Amit M. ;

Kauffman, Michael ;

Siu, Lillian L. ;

Mirza, Mansoor Raza .

JOURNAL OF CLINICAL ONCOLOGY, 2013, 31 (15)

[44] First-in-human (FIH) study of E7130 in patients (pts) with advanced solid tumors: Primary result of dose-escalation part [J].

Doi, T. ;

Matsubara, N. ;

Naito, Y. ;

Kuboki, Y. ;

Harano, K. ;

Ono, M. ;

Urasaki, T. ;

Ohmoto, A. ;

Hisai, T. ;

Mikubo, A. ;

Ikezawa, H. ;

Shiba, S. ;

Ito, K. ;

Asano, O. ;

Takahashi, S. .

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[45] Phase 1/2 first-in-human (FIH) study of CPI-0209, a novel small molecule inhibitor of enhancer of zeste homolog 2 (EZH2) in patients with advanced tumors. [J].

Lakhani, Nehal J. ;

Gutierrez, Martin ;

Duska, Linda R. ;

Do, Khanh Tu ;

Sharma, Manish ;

Gandhi, Leena ;

Papadopoulos, Kyriakos P. ;

Truong, Jennifer ;

Fan, Xiaolin ;

Lee, Ji Hyun ;

Bobba, Suresh ;

Rippley, Ronda ;

Wu, Rentian ;

Cui, Jike ;

Sun, Kaiming ;

Wang, Jing Y. ;

Trojer, Patrick ;

Rasco, Drew W. .

JOURNAL OF CLINICAL ONCOLOGY, 2021, 39 (15)

[46] A first-in-human study of pegylated recombinant human IL-10 (AM0010), daily administered for four months in selected advanced solid tumors. [J].

Bauer, Todd Michael ;

Papadopoulos, Kyriakos P. ;

Autio, Karen A. ;

Ott, Patrick Alexander ;

Whiteside, Melinda ;

Oft, Martin ;

Infante, Jeffrey R. ;

Hod, F. Stephen ;

Wolchok, Jedd I. .

JOURNAL OF CLINICAL ONCOLOGY, 2014, 32 (15)

[47] TRIAL IN PROGRESS: PHASE 1 FIRST-IN-HUMAN STUDY OF XL092 ADMINISTERED ALONE OR IN COMBINATION WITH IMMUNE CHECKPOINT INHIBITORS IN PATIENTS WITH INOPERABLE LOCALLY ADVANCED OR METASTATIC SOLID TUMORS [J].

Patnaik, Amita ;

Subbiah, Vivek ;

Shapiro, Geoffrey ;

Pal, Sumanta ;

Agarwal, Neeraj ;

Wentzel, Kristopher ;

Li, Jing ;

McIlvaine, Elizabeth ;

Waldes, Jana ;

Cha, Edward ;

Tadjalli-Mehr, Keyvan ;

Sharma, Manish .

JOURNAL FOR IMMUNOTHERAPY OF CANCER, 2021, 9 :A544-A544

[48] A first-in-human study of the dual A2A/A2B adenosine receptor antagonist M1069 in patients with advanced solid tumors. [J].

Siu, Lillian L. ;

Gutierrez, Martin E. ;

Guezel, Guelseren ;

Ruth, Katia ;

Hu, Ping ;

Kitzing, Thomas ;

Habermehl, Christina ;

McKean, Meredith .

CANCER RESEARCH, 2022, 82 (12)

[49] A first-in-human phase 1 dose escalation study of FF-10850 (liposomal topotecan) in patients with advanced solid tumors. [J].

Matulonis, Ursula A. ;

Janku, Filip ;

Moser, Justin C. ;

Fu, Siqing ;

Wages, David S. ;

Wheeler, Catherine A. ;

Mori, Mikinaga ;

Shimoyama, Susumu ;

Yamada, Naoki ;

Subach, Ruth Ann ;

Cheung, Kin ;

Madden, Timothy ;

Maier, Gary ;

Johansen, Mary ;

Falchook, Gerald Steven .

JOURNAL OF CLINICAL ONCOLOGY, 2022, 40 (16)

[50] A first-in-human phase I study to evaluate the fully human monoclonal antibody OMP-59R5 (anti-Notch2/3) administered intravenously to patients with advanced solid tumors [J].

Tolcher, Anthony W. ;

Chugh, Rashmi ;

Chambers, Glenda ;

Thorpe, Villette ;

Dupont, Jakob ;

Hill, Dawn ;

Xu, Lu ;

Kapoun, Ann ;

Smith, David C. .

JOURNAL OF CLINICAL ONCOLOGY, 2012, 30 (15)

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