Indocyanine green plasma disappearance rate as dynamic liver function test in critically ill patients

被引：69
作者：
Halle, B. M. [1 ]
Poulsen, T. D. [1 ]
Pedersen, H. P. [1 ]
机构：
[1] Copenhagen Univ Hosp Roskilde, Dept Anesthesia & Intens Care, Roskilde, Region Zealand, Denmark
来源：
ACTA ANAESTHESIOLOGICA SCANDINAVICA | 2014年 / 58卷 / 10期
关键词：
PULSE SPECTROPHOTOMETRY; HEPATIC RESECTION; HEPATECTOMY; DYSFUNCTION; TRANSPLANTATION; RETENTION; PRESSURE; FAILURE; LIMON;
D O I：
10.1111/aas.12406
中图分类号：
R614 [麻醉学];
学科分类号：
100217 ;
摘要：
BackgroundIndocyanine green (ICG) is a water-soluble fluorescent dye that is bound to plasma protein when administered intravenously. Removal of ICG from the blood depends on hepatic blood flow, function of the parenchymal cells and biliary excretion. ICG elimination is described as a useful dynamic liver function test. MethodsIn this review, we looked at the most recent literature to clarify why ICG is useful in critically ill patients, the validity of the ICG plasma disappearance rate (ICG-PDR) measured transcutaneously and whether ICG-PDR has any prognostic value. ConclusionIn conclusion, measuring ICG-PDR is a valuable method for dynamic assessment of liver function, and is found to be a valuable prognostic tool in predicting survival for septic patients, patients presenting with acute liver failure and critically ill patients.
引用
收藏
页码：1214 / 1219
页数：6
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