Fluorogenic Sensing of Carcinogenic Bisphenol A using Aptamer-Capped Mesoporous Silica Nanoparticles

被引：38

作者：

Ribes, Angela ^{[1
,2
]}

Aznar, Elena ^{[1
,2
]}

Bernardos, Andrea ^{[1
,2
]}

Dolores Marcos, M. ^{[1
,2
,4
]}

Amoros, Pedro ^{[3
]}

Martinez-Manez, Ramon ^{[1
,2
,4
]}

Sancenon, Felix ^{[1
,2
,4
]}

机构：

[1] Univ Valencia, Univ Politecn Valencia, Inst Interuniv Invest Reconocimiento Mol & Desarr, Cami Vera S-N, Valencia 46022, Spain

[2] CIBER BBN, Zaragoza, Spain

[3] Univ Valencia, Inst Ciencia Mat ICMUV, POB 22085, Valencia 46071, Spain

[4] Univ Politecn Valencia, Dept Quim, Cami Vera S-N, E-46022 Valencia, Spain

来源：

CHEMISTRY-A EUROPEAN JOURNAL | 2017年 / 23卷 / 36期

关键词：

aptamer; bisphenol a; fluorogenic sensing; gated nanomaterials; mesoporous silica nanoparticles; CHROMATOGRAPHY-MASS SPECTROMETRY; SOLID-PHASE EXTRACTION; LIQUID-CHROMATOGRAPHY; DRUG-DELIVERY; ULTRASENSITIVE DETECTION; GOLD NANOPARTICLES; GATED MATERIALS; DRINKING-WATER; EPOXY-RESINS; SAMPLES;

D O I：

10.1002/chem.201701024

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Mesoporous silica nanoparticles loaded with rhodamine B and capped with a bisphenol A aptamer were used for the selective and sensitive detection of this lethal chemical. The pores of the nanoparticles are selectively opened in the presence of bisphenol A (through its selective coordination with the aptamer) with subsequent rhodamine B delivery. With this capped material a limit of detection as low as 3.5 mu m of bisphenol A was measured.

引用

页码：8581 / 8584

页数：4

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