Fluorogenic Sensing of Carcinogenic Bisphenol A using Aptamer-Capped Mesoporous Silica Nanoparticles

被引：38
作者：
Ribes, Angela [1 ,2 ]
Aznar, Elena [1 ,2 ]
Bernardos, Andrea [1 ,2 ]
Dolores Marcos, M. [1 ,2 ,4 ]
Amoros, Pedro [3 ]
Martinez-Manez, Ramon [1 ,2 ,4 ]
Sancenon, Felix [1 ,2 ,4 ]
机构：
[1] Univ Valencia, Univ Politecn Valencia, Inst Interuniv Invest Reconocimiento Mol & Desarr, Cami Vera S-N, Valencia 46022, Spain
[2] CIBER BBN, Zaragoza, Spain
[3] Univ Valencia, Inst Ciencia Mat ICMUV, POB 22085, Valencia 46071, Spain
[4] Univ Politecn Valencia, Dept Quim, Cami Vera S-N, E-46022 Valencia, Spain
来源：
CHEMISTRY-A EUROPEAN JOURNAL | 2017年 / 23卷 / 36期
关键词：
aptamer; bisphenol a; fluorogenic sensing; gated nanomaterials; mesoporous silica nanoparticles; CHROMATOGRAPHY-MASS SPECTROMETRY; SOLID-PHASE EXTRACTION; LIQUID-CHROMATOGRAPHY; DRUG-DELIVERY; ULTRASENSITIVE DETECTION; GOLD NANOPARTICLES; GATED MATERIALS; DRINKING-WATER; EPOXY-RESINS; SAMPLES;
D O I：
10.1002/chem.201701024
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Mesoporous silica nanoparticles loaded with rhodamine B and capped with a bisphenol A aptamer were used for the selective and sensitive detection of this lethal chemical. The pores of the nanoparticles are selectively opened in the presence of bisphenol A (through its selective coordination with the aptamer) with subsequent rhodamine B delivery. With this capped material a limit of detection as low as 3.5 mu m of bisphenol A was measured.
引用
收藏
页码：8581 / 8584
页数：4
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