Synthesis of 4-(5-aryl-1 3,4-oxadiazol-2-yl)phenyl-hydrazine derivatives from 3-(4-hydrazinocarbonyl-phenyl)sydnones

被引：2
作者：
Chang, Hung-Te
Chiang, Kuo-Chen
Wong, Fung Fuh
Huang, Chun-Sheng
Liao, Yang-Ming
Kuo, Wen-Fa
Won, Shaw-Bing
Yeh, Mou-Yung
机构：
[1] China Med Univ, Grad inst Pharmaceut Chem, Taichung 40402, Taiwan
[2] Natl Cheng Kung Univ, Dept Chem, Tainan 70101, Taiwan
[3] Natl Cheng Kung Univ, Dept Resources Engn, Tainan 70101, Taiwan
[4] Natl Cheng Kung Univ, Sustainable Environm Res Ctr, Tainan 709, Taiwan
来源：
HETEROATOM CHEMISTRY | 2007年 / 18卷 / 04期
关键词：
D O I：
10.1002/hc.20318
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
The synthesis of potential fluorescent active 4-(5-aryl-1,3,4-oxadiazol-2-yl)phenylhydrazine derivatives was accomplished in three steps. The key step was the dehydration cyclization of 1,2-diacylhydrazines to form the 1,3,4-oxadiazole ring by use of acetic anhydride/perchloric acid mixture as the dehydrating agent. The sydnone moiety served as the masked hydrazines, which could be demasked by HCl for further application. (c) 2007 Wiley Periodicals, Inc.
引用
收藏
页码：438 / 442
页数：5
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