A novel cross-linking reagent for bovine hemoglobin modification

被引：2
|
作者：
He, ML [1 ]
Lu, XL [1 ]
Zhao, DX [1 ]
Su, ZG [1 ]
机构：
[1] Chinese Acad Sci, Inst Proc Engn, Natl Lab Biochem Engn, Beijing 100080, Peoples R China
来源：
BIOTECHNOLOGY LETTERS | 2003年 / 25卷 / 04期
关键词：
bovine hemoglobin; cross-linking reagent; modification; polyethylene glycol;
D O I：
10.1023/A:1022353711956
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
A novel cross-linking reagent, methoxypolyethelene glycol-glutamic acid, was synthesized and used to modify bovine hemoglobin. Bis-tetrameric hemoglobin with moderate affinity for O-2 was obtained under the controlled reaction conditions.
引用
收藏
页码：327 / 330
页数：4
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