A new antiplasmodial coumarin from Toddalia asiatica roots

被引:64
|
作者
Oketch-Rabah, HA
Mwangi, JW
Lisgarten, J
Mberu, EK
机构
[1] Univ Nairobi, Coll Hlth Sci, Fac Pharm, Dept Pharmacol & Pharmacognosy, Nairobi, Kenya
[2] Univ London Birkbeck Coll, Dept Crystallog, London WC1E 7HX, England
[3] Wellcome Trust Res Labs, Nairobi, Kenya
关键词
Toddalia asiatica; antimalarial activity; coumarins;
D O I
10.1016/S0367-326X(00)00222-7
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
A new antiplasmodial coumarin, 5,7-dimethoxy-8-(3'-hydroxy-3'-methyl-1'-butene)-coumarin (1), has been isolated from the roots of Toddalia asiatica. This finding supports the traditional use of this plant for the treatment of malaria. (C) 2000 Elsevier Science B.V. All rights reserved.
引用
收藏
页码:636 / 640
页数:5
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