Spectrophotometric estimation of olmesartan medoxomil and hydrochlorothiazide in tablet

被引:16
作者
Rote, A. R. [1 ]
Bari, P. D. [1 ]
机构
[1] MGVs Pharm Coll, Dept Pharmaceut Chem, Nasik 422003, India
关键词
Hydrochlorothiazide; Olmesartan medoxomil; UV spectrophotometry;
D O I
10.4103/0250-474X.62245
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
A simultaneous determination of olmesartan medoxomil and hydrochlorothiazide by absorption ratio spectrophotometric method has been developed in combined tablet dosage form. The method is based on measurements of absorbance at isoabsoptive point. The Beers law obeys in the range of 10-30 mg/ml for both olmesartan medoxomil and hydrochlorothiazide respectively. The proposed method was validated by performing recovery study and statistically.
引用
收藏
页码:111 / 113
页数:3
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