IN VITRO STUDIES OF THE USE OF SOME MEDICINAL HERBALS LEAVES AGAINST ANTIDEPRESSANT, ANALGESIC ACTIVITY, AND ANTI-INFLAMMATORY ACTIVITY

被引:0
作者
Sharma, M. C. [1 ]
Sharma, S. [1 ]
Kohli, D. V. [1 ]
机构
[1] Devi Ahilya Vishwavidyalaya, Sch Pharm, Indore 452017, Madhya Pradesh, India
关键词
Annona Squamosa; Azadiracta Indica; Anti-Inflammatory activity; Analgesic activity; Antidepressant activity;
D O I
暂无
中图分类号
TB3 [工程材料学];
学科分类号
0805 ; 080502 ;
摘要
The aim of present study was to assess the anti-inflammatory activity of polyherbal formulation of leaves of Annona squamosa, Azadiracta indica. The mature green leaves of Annona squamosa, Azadiracta indica were collected and authenticated. Extractions of dried leaves and rhizome were carried out with ethanol in soxhlet apparatus. The polyherbal formulation showed the significant anti-inflammatory activity comparable to the standard drug Indomethacin against carrageenan induced rat paw edema method. The polyherbal formulation reduced the inflammation induced by carrageenan by 53.0% and 47.0% on oral administration at 100 mg/kg and 200 mg/kg respectively as compared to the control treated group an analgesic activity comparable to the standard drug tramadol HCl.
引用
收藏
页码:131 / 134
页数:4
相关论文
共 50 条
[21]   Synthesis and in vivo analgesic and anti-inflammatory activity of some bi heterocyclic coumarin derivatives [J].
Ghate, M ;
Kusanur, RA ;
Kulkarni, MV .
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2005, 40 (09) :882-887
[22]   Studies on the anti-inflammatory and analgesic activity of Cedrus deodara (Roxb.) Loud. wood oil [J].
Shinde, UA ;
Phadke, AS ;
Nair, AM ;
Mungantiwar, AA ;
Dikshit, VJ ;
Saraf, MN .
JOURNAL OF ETHNOPHARMACOLOGY, 1999, 65 (01) :21-27
[23]   Topical anti-inflammatory activity of Bauhinia tarapotensis leaves [J].
Sosa, S ;
Braca, A ;
Altinier, G ;
Della Loggia, R ;
Morelli, I ;
Tubaro, A .
PHYTOMEDICINE, 2002, 9 (07) :646-653
[24]   Antinociceptive and anti-inflammatory activity of Sida rhomboidea leaves [J].
Venkatesh, S ;
Reddy, YSR ;
Suresh, B ;
Reddy, BM ;
Ramesh, M .
JOURNAL OF ETHNOPHARMACOLOGY, 1999, 67 (02) :229-232
[25]   Topical anti-inflammatory activity of Solanum corymbiflorum leaves [J].
Piana, Mariana ;
Camponogara, Camila ;
Boligon, Aline Augusti ;
Machado, Michel Mansur ;
de Brum, Thiele Faccim ;
Oliveira, Sara Marchesan ;
Bauermann, Liliane de Freitas .
JOURNAL OF ETHNOPHARMACOLOGY, 2016, 179 :16-21
[26]   Topical anti-inflammatory activity of some Asian medicinal plants used in dermatological disorders [J].
Cuéllar, MJ ;
Giner, RM ;
Recio, MC ;
Máñez, S ;
Ríos, JL .
FITOTERAPIA, 2001, 72 (03) :221-229
[27]   Topical anti-inflammatory activity of Solenostemma argel leaves [J].
Innocenti, G ;
Dall'Acqua, S ;
Sosa, S ;
Altinier, G ;
Della Loggia, R .
JOURNAL OF ETHNOPHARMACOLOGY, 2005, 102 (02) :307-310
[28]   The Anti-inflammatory Activity of Pentacyclic Triterpenes in Vitro [J].
Bai, Liming ;
Meng, Fanxu ;
Zhao, Lijie ;
Zhao, Ming .
APPLIED MECHANICS AND MECHANICAL ENGINEERING II, PTS 1 AND 2, 2012, 138-139 :1174-1178
[29]   iNOS/PGE2 inhibitors as a novel template for analgesic/anti-inflammatory activity: Design, synthesis, in vitro biological activity and docking studies [J].
Erdogan, Ayca ;
Ozhan, Yagmur ;
Sipahi, Hande ;
Gurdal, Enise Ece ;
Sippl, Wolfgang ;
Koksal, Meric .
ARCHIV DER PHARMAZIE, 2024, 357 (12)
[30]   ANTIFUNGAL, ANTI-INFLAMMATORY AND ANALGESIC ACTIVITY OF AILANTHUS EXCELSA BARK [J].
Patil, Sharanabasappa B. ;
Reddy, Upender C. H. ;
Goudgaon, N. M. .
INTERNATIONAL JOURNAL OF PHARMACEUTICAL SCIENCES AND RESEARCH, 2010, 1 (12) :119-122