Immunotherapy in hematologic malignancies: past, present, and future

被引:93
作者
Im, Annie [1 ]
Pavletic, Steven Z. [2 ]
机构
[1] Univ Pittsburgh, Inst Canc, 5150 Ctr Ave,Suite 554, Pittsburgh, PA 15213 USA
[2] Natl Inst Hlth, Natl Canc Inst, Bethesda, MD USA
关键词
Immunotherapy; Hematologic malignancies; Stem cell transplantation; CHIMERIC-ANTIGEN-RECEPTOR; STEM-CELL TRANSPLANTATION; ENGAGER BITE ANTIBODY; MODIFIED T-CELLS; ACUTE LYMPHOBLASTIC-LEUKEMIA; ACUTE MYELOID-LEUKEMIA; B-CELL; BRENTUXIMAB VEDOTIN; HODGKIN-LYMPHOMA; OPEN-LABEL;
D O I
10.1186/s13045-017-0453-8
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
The field of immunotherapy in cancer treatments has been accelerating over recent years and has entered the forefront as a leading area of ongoing research and promising therapies that have changed the treatment landscape for a variety of solid malignancies. Prior to its designation as the Science Breakthrough of the Year in 2013, cancer immunotherapy was active in the treatment of hematologic malignancies. This review provides a broad overview of the past, present, and potential future of immunotherapy in hematologic malignancies.
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页数:10
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