SLP-76 is dephosphorylated by SHP-1 and regulates BCR-mediated signaling in B cells

被引:0
|
作者
Mizuno, K [1 ]
Watanabe, N [1 ]
Ogimoto, M [1 ]
Yakura, H [1 ]
机构
[1] Tokyo Metropolitan Inst Neurosci, Dept Immunol, Tokyo 1838526, Japan
来源
FASEB JOURNAL | 2003年 / 17卷 / 07期
关键词
D O I
暂无
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
引用
收藏
页码:C207 / C207
页数:1
相关论文
共 50 条
  • [1] SLP-76, a substrate for SHP-1, regulates BCR-induced JNK activation
    Mizuno, K
    Watanabe, N
    Ogimoto, M
    Yakura, H
    FASEB JOURNAL, 2004, 18 (04): : A51 - A51
  • [2] SHP-1 dephsohprylates SHP-1 and SLP-76, thereby inactivating SHP-1 in mast cells
    Mizuno, Kazuya
    Ozawa, Tomoko
    Nakata, Kazuko
    Yakura, Hidetaka
    JOURNAL OF IMMUNOLOGY, 2006, 176 : S320 - S321
  • [3] SLP-76 is a direct substrate of SHP-1 recruited to killer cell inhibitory receptors
    Binstadt, BA
    Billadeau, DD
    Jevremovic, D
    Williams, BL
    Fang, N
    Yi, TL
    Koretzky, GA
    Abraham, RT
    Leibson, PJ
    JOURNAL OF BIOLOGICAL CHEMISTRY, 1998, 273 (42) : 27518 - 27523
  • [4] SLP-76 regulates Fcγ receptor and integrin signaling in neutrophils
    Newbrough, SA
    Mocsai, A
    Clemens, RA
    Wu, JN
    Silverman, MA
    Singer, AL
    Lowell, CA
    Koretzky, GA
    IMMUNITY, 2003, 19 (05) : 759 - 769
  • [5] Hematopoietic cell phosphatase, SHP-1, is constitutively associated with the SH2 domain-containing leukocyte protein, SLP-76, in B cells
    Mizuno, K
    Katagiri, T
    Hasegawa, K
    Ogimoto, M
    Yakura, H
    JOURNAL OF EXPERIMENTAL MEDICINE, 1996, 184 (02): : 457 - 463
  • [6] SLP-76 is recruited to CD22 and dephosphorylated by SHP-1, thereby regulating B cell receptor-induced c-Jun N-terminal kinase activation
    Mizuno, K
    Tagawa, Y
    Watanabe, N
    Ogimoto, M
    Yakura, H
    EUROPEAN JOURNAL OF IMMUNOLOGY, 2005, 35 (02) : 644 - 654
  • [7] Disruption of SLP-76 interaction with Gads inhibits dynamic clustering of SLP-76 and FcεRI signaling in mast cells
    Silverman, MA
    Shoag, J
    Wu, J
    Koretzky, GA
    MOLECULAR AND CELLULAR BIOLOGY, 2006, 26 (05) : 1826 - 1838
  • [8] HIV-1 Nef limits communication between LAT and Slp-76 to reduce formation of Slp-76 signaling microclusters
    Abraham, Libin
    Bankhead, Peter
    Pan, Xiaoyu
    Engel, Ulrike
    Fackler, Oliver
    JOURNAL OF IMMUNOLOGY, 2012, 188
  • [9] SHP-1 dephosphorylates BLNK/SLP-65 and selectively regulates JNK activation in B cells.
    Mizuno, K
    Tagawa, Y
    Mitomo, K
    Arimura, Y
    Hatano, N
    Katagiri, T
    Ogimoto, M
    Yakura, H
    FASEB JOURNAL, 2000, 14 (06): : A967 - A967
  • [10] Multipoint Binding of the SLP-76 SH2 Domain to ADAP Is Critical for Oligomerization of SLP-76 Signaling Complexes in Stimulated T Cells
    Coussens, Nathan P.
    Hayashi, Ryo
    Brown, Patrick H.
    Balagopalan, Lakshmi
    Balbo, Andrea
    Akpan, Itoro
    Houtman, Jon C. D.
    Barr, Valarie A.
    Schuck, Peter
    Appella, Ettore
    Samelson, Lawrence E.
    MOLECULAR AND CELLULAR BIOLOGY, 2013, 33 (21) : 4140 - 4151