Investigation of probable relationship between Toxoplasma gondii and cryptogenic epilepsy

被引：51

作者：

Yazar, S ^{[1
]}

Arman, F

Yalçin, S

Dimirtas, F

Yaman, O

Sahin, I

机构：

[1] Erciyes Univ, Fac Med, Dept Parasitol, Kayseri, Turkey

[2] Erciyes Univ, Fac Med, Dept Neurol, Kayseri, Turkey

来源：

SEIZURE-EUROPEAN JOURNAL OF EPILEPSY | 2003年 / 12卷 / 02期

关键词：

Toxoplasma gondii; cryptogenic epilepsy; ELISA;

D O I：

10.1016/S1059-1311(02)00256-X

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Purpose: Cryptogenic epilepsy, defines a group of epilepsy syndromes for which an aetiology is unknown but an underlying brain disease is suspected. We selected patients in this subgroup of epilepsy and investigated the sero-positivity rate for anti-Toxoplasma IgG antibodies by Enzyme Linked Immunosorbent Assay (ELISA). We investigated the probable relationship between Toxoplasma gondii and cryptogenic epilepsy. Methods: We selected 50 patients with cryptogenic epilepsy, 50 patients with known cause epilepsy and 50 healthy volunteers and investigated the sero-positivity rate for anti-Toxoplasma IgG antibodies by ELISA. Results: The sero-positivity rate for anti-Toxoplasma IgG antibodies among cryptogenic epilepsy patients (52%) was found to be higher than healthy volunteers (18%) and known cause epilepsy patients (22%) with statistical significance, (X-2 = 18.095, P < 0.01). Conclusion: There might be a causal relationship between chronic toxoplasmosis and the aetiology of cryptogenic epilepsy. (C) 2002 BEA Trading Ltd. Published by Elsevier Science Ltd. All rights reserved,

引用

页码：107 / 109

页数：3

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