A two-photon ESIPT based fluorescence probe for specific detection of hypochlorite

被引：79

作者：

Chen, Liyan ^{[1
]}

Park, Sang Jun ^{[2
]}

Wu, Di ^{[1
]}

Kim, Hwan Myung ^{[2
]}

Yoon, Juyoung ^{[1
]}

机构：

[1] Ewha Womans Univ, Dept Chem & Nano Sci, Seoul 120750, South Korea

[2] Ajou Univ, Dept Chem & Energy Syst Res, Suwon, South Korea

来源：

DYES AND PIGMENTS | 2018年 / 158卷

基金：

新加坡国家研究基金会;

关键词：

ESIPT; Hypochlorite; Two-photon; Living cells; Tissue imaging; INTRAMOLECULAR PROTON-TRANSFER; REAL-TIME DISCRIMINATION; TURN-ON PROBE; LIVING CELLS; SELECTIVE DETECTION; LIVE CELLS; REACTIVE OXYGEN; RAPID DETECTION; FREE-RADICALS; FAST-RESPONSE;

D O I：

10.1016/j.dyepig.2018.01.027

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

Hypochlorous acid (HOCl) is one important member of reactive oxygen species (ROS) familyresponsible for various human diseases. Although many contributions have been made to develop fluorescent probes for sensing HOCl, many of them suffer small Stokes shifts, sophisticated synthetic procedure, and slow reaction rate. In the current study, we designed and synthesized an ESIPT based fluorescence probe with diaminomeleonitrile (DMN) as reactive site. The probe can detect HOCl with high selectivity and sensitivity. It also has large Stokes shift and rapid reaction rate. Moreover, it can be utilized to monitor exogenous and endogenous HOCl in living cells and tissues via two-photon microscopy.

引用

页码：526 / 532

页数：7

共 89 条

[1] Synthesis and fluorescence properties of benzoxazole-1,4-dihydropyridine dyads achieved by a multicomponent reaction [J].

Affeldt, Ricardo Ferreira ;

de Amorim Borges, Antonio Cesar ;

Russowsky, Dennis ;

Rodembusch, Fabiano Severo .

NEW JOURNAL OF CHEMISTRY, 2014, 38 (09) :4607-4614

[2] Tetrasubstituted imidazole core containing ESIPT fluorescent chemodosimeter for selective detection of cyanide in different medium [J].

Ali, Rashid ;

Razi, Syed S. ;

Srivastava, Priyanka ;

Misra, Arvind .

SENSORS AND ACTUATORS B-CHEMICAL, 2015, 221 :1236-1247

[3] pH-Dependent Si-Fluorescein Hypochlorous Acid Fluorescent Probe: Spirocycle Ring-Opening and Excess Hypochlorous Acid-Induced Chlorination [J].

Best, Quinn A. ;

Sattenapally, Narsimha ;

Dyer, Daniel J. ;

Scott, Colleen N. ;

McCarroll, Matthew E. .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2013, 135 (36) :13365-13370

[4]

Chan J, 2012, NAT CHEM, V4, P973, DOI [10.1038/NCHEM.1500, 10.1038/nchem.1500]

[5] Selective Hg2+ signaling via dithiane to aldehyde conversion of an ESIPT fluorophore [J].

Chang, In Jung ;

Hwang, Keum Saem ;

Chang, Suk-Kyu .

DYES AND PIGMENTS, 2017, 137 :69-74

[6] An ESIPT based fluorescence probe for ratiometric monitoring of nitric oxide [J].

Chen, Liyan ;

Wu, Di ;

Yoon, Juyoung .

SENSORS AND ACTUATORS B-CHEMICAL, 2018, 259 :347-353

[7] An ESIPT-Based Fluorescence Probe for Colorimetric, Ratiometric, and Selective Detection of Phosgene in Solutions and the Gas Phase [J].

Chen, Liyan ;

Wu, Di ;

Kim, Jong-Man ;

Yoon, Juyoung .

ANALYTICAL CHEMISTRY, 2017, 89 (22) :12596-12601

[8] A two-photon fluorescent probe for specific detection of hydrogen sulfide based on a familiar ESIPT fluorophore bearing AIE characteristics [J].

Chen, Liyan ;

Wu, Di ;

Lim, Chang Su ;

Kim, Dayoung ;

Nam, Sang-Jip ;

Lee, Woolin ;

Kim, Gyungmi ;

Kim, Hwan Myung ;

Yoon, Juyoung .

CHEMICAL COMMUNICATIONS, 2017, 53 (35) :4791-4794

[9] Highly sensitive and selective ESIPT-based fluorescent probes for detection of Pd2+ with large Stocks shifts [J].

Chen, Tiantian ;

Wei, Tingwen ;

Zhang, Zhijie ;

Chen, Yahui ;

Qiang, Jian ;

Wang, Fang ;

Chen, Xiaoqiang .

DYES AND PIGMENTS, 2017, 140 :392-398

[10] A turn-on fluorescent probe for hypochlorous acid based on HOCl-promoted removal of the C=N bond in BODIPY-hydrazone [J].

Chen, Wei-Chieh ;

Venkatesan, Parthiban ;

Wu, Shu-Pao .

NEW JOURNAL OF CHEMISTRY, 2015, 39 (09) :6892-6898

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