Antibacterial, antiprotozoal and antioxidant activity of five plants used in Izabal for infectious diseases

被引：41
作者：
Navarro, MC
Montilla, MP
Cabo, MM
Galisteo, M
Cáceres, A
Morales, C
Berger, I
机构：
[1] Univ Granada, Fac Pharm, Dept Pharmacol, E-18071 Granada, Spain
[2] Univ San Carlos, Fac Chem Sci & Pharm, USAC, Guatemala City, Guatemala
[3] Univ Vienna, Inst Pharmacognosy, A-1010 Vienna, Austria
来源：
PHYTOTHERAPY RESEARCH | 2003年 / 17卷 / 04期
关键词：
medicinal plants; antibacterial; antiprotozoal; antioxidant; free radical scavenger; lipid peroxidation;
D O I：
10.1002/ptr.1134
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
Methanol and aqueous extracts from five plant species, used in traditional medicine in Guatemala for the treatment of microbial infections, were tested in vitro for their ability to scavenge DPPH, OH. and O-2(-) radicals and to inhibit lipoperoxidation (LPO) in order to establish a relationship between their antioxidant activities and their effects against infectious agents. Acalypha guatemalensis, Ocimum micranthum and Smilax spinosa possessed a significant activity against both the three free radicals assayed and LPO; Guazuma ulmifolia showed effects against DPPH and OH.. Piper auritum showed no activity. These extracts were also evaluated for antibacterial and antiprotozoal activities. A. guatemalensis showed activity against Pseudomonas aeruginosa; S. spinosa was active against Salmonella typhi, and A. guatemalensis, and S. spinosa against Trypanosoma cruzi or Leishmania spp. Copyright (C) 2003 John Wiley Sons, Ltd.
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页码：325 / 329
页数：5
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