Effect of GLIM-defined malnutrition on postoperative clinical outcomes in patients with colorectal cancer

被引：33
作者：
Song, Hao-Nan [1 ]
Wang, Wen-Bin [1 ]
Luo, Xin [1 ]
Huang, Dong-Dong [1 ]
Ruan, Xiao-Jiao [1 ]
Xing, Chun-Gen [2 ]
Chen, Wei-Zhe [3 ]
Dong, Qian-Tong [1 ,2 ]
Chen, Xiao-Lei [1 ]
机构：
[1] Wenzhou Med Univ, Dept Gastrointestinal Surg, Affiliated Hosp 1, Wenzhou, Zhejiang, Peoples R China
[2] Soochow Univ, Dept Gen Surg, Affiliated Hosp 2, Suzhou, Jiangsu, Peoples R China
[3] Tongji Univ, Shanghai Peoples Hosp 10, Dept Gastrointestinal Surg, Sch Med, Shanghai, Peoples R China
来源：
JAPANESE JOURNAL OF CLINICAL ONCOLOGY | 2022年 / 52卷 / 05期
关键词：
GLIM; malnutrition; colorectal cancer; complication; overall survival; disease-free survival; BODY-COMPOSITION; GRIP STRENGTH; MUSCLE MASS; NUTRITION; MORTALITY; SOCIETY; COHORT; HEALTH;
D O I：
10.1093/jjco/hyab215
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Preoperative Global Leadership Initiative on Malnutrition-defined malnutrition is associated with postoperative complications, overall survival and disease-free survival in colorectal cancer patients after radical resection surgery. Background Malnutrition is common in colorectal cancer patients. Malnutrition is recognized as a risk factor for adverse postoperative outcomes, yet there are no consistent diagnostic criteria for it. Thus, the Global Leadership Initiative on Malnutrition published new universal criteria. We aimed to investigate the prevalence of malnutrition with the application of Global Leadership Initiative on Malnutrition criteria, and explore the correlations between Global Leadership Initiative on Malnutrition-defined malnutrition and postoperative clinical outcomes in colorectal cancer patients. Methods We included a cohort of 918 patients who underwent radical resection surgery for colorectal cancer from July 2014 to October 2019. Malnutrition was diagnosed based on the Global Leadership Initiative on Malnutrition criteria. The associations between nutritional status and postoperative clinical outcomes were analyzed by the Kaplan-Meier method, logistic and Cox regression analyses. Results Among the included patients, 23.6% were diagnosed as malnutrition based on Global Leadership Initiative on Malnutrition criteria. Global Leadership Initiative on Malnutrition-defined malnutrition was associated with total postoperative complications [odds ratio: 1.497 (1.042-2.152), P = 0.029]. Further, Global Leadership Initiative on Malnutrition-diagnosed malnutrition was an independent risk factor for overall survival [hazard ratio: 1.647 (1.048-2.587), P = 0.030] and disease-free survival [hazard ratio: 1.690 (1.169-2.441), P = 0.005]. Conclusions The Global Leadership Initiative on Malnutrition criteria is effective to assess malnutrition. Preoperative malnutrition is associated with postoperative complications, overall survival and disease-free survival in colorectal cancer patients after radical resection surgery.
引用
收藏
页码：466 / 474
页数：9
相关论文
共 39 条
[1]   The relation between Malnutrition Universal Screening Tool (MUST), computed tomography-derived body composition, systemic inflammation, and clinical outcomes in patients undergoing surgery for colorectal cancer [J].
Almasaudi, Arwa S. ;
McSorley, Stephen T. ;
Dolan, Ross D. ;
Edwards, Christine A. ;
McMillan, Donald C. .
AMERICAN JOURNAL OF CLINICAL NUTRITION, 2019, 110 (06) :1327-1334
[2]  
Cederholm T, 2019, CLIN NUTR, V38, P1, DOI [10.1002/jcsm.12383, 10.1016/j.clnu.2019.02.033, 10.1016/j.clnu.2018.08.002, 10.1002/jpen.1440]
[3]   Diagnostic criteria for malnutrition - An ESPEN Consensus Statement [J].
Cederholm, T. ;
Bosaeus, I. ;
Barazzoni, R. ;
Bauer, J. ;
Van Gossum, A. ;
Klek, S. ;
Muscaritoli, M. ;
Nyulasi, I. ;
Ockenga, J. ;
Schneider, S. M. ;
de van der Schueren, M. A. E. ;
Singer, P. .
CLINICAL NUTRITION, 2015, 34 (03) :335-340
[4]   Diagnosis of malnutrition in patients with gastrointestinal diseases: recent observations from a Global Leadership Initiative on Malnutrition perspective [J].
Cederholm, Tommy ;
Krznaric, Zeljko ;
Pirlich, Matthias .
CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE, 2020, 23 (05) :361-366
[5]   Cancer Statistics in China, 2015 [J].
Chen, Wanqing ;
Zheng, Rongshou ;
Baade, Peter D. ;
Zhang, Siwei ;
Zeng, Hongmei ;
Bray, Freddie ;
Jemal, Ahmedin ;
Yu, Xue Qin ;
He, Jie .
CA-A CANCER JOURNAL FOR CLINICIANS, 2016, 66 (02) :115-132
[6]  
Contreras-Bolivar V., 2019, NUTRIENTS, V11, P9
[7]   Hospital malnutrition in Latin America: A systematic review [J].
Correia, Maria Isabel T. D. ;
Ignacio Perman, Mario ;
Waitzberg, Dan Linetzky .
CLINICAL NUTRITION, 2017, 36 (04) :958-967
[8]   The impact of malnutrition on morbidity, mortality, length of hospital stay and costs evaluated through a multivariate model analysis [J].
Correia, MITD ;
Waitzberg, DL .
CLINICAL NUTRITION, 2003, 22 (03) :235-239
[9]   Malnutrition Screening and Assessment in the Cancer Care Ambulatory Setting: Mortality Predictability and Validity of the Patient-Generated Subjective Global Assessment Short form (PG-SGA SF) and the GLIM Criteria [J].
De Groot, Lynette M. ;
Lee, Gahee ;
Ackerie, Antoinette ;
van der Meij, Barbara S. .
NUTRIENTS, 2020, 12 (08) :1-13
[10]   Longitudinal study of muscle strength, quality, and adipose tissue infiltration [J].
Delmonico, Matthew J. ;
Harris, Tamara B. ;
Visser, Marjolein ;
Park, Seok Won ;
Conroy, Molly B. ;
Velasquez-Mieyer, Pedro ;
Boudreau, Robert ;
Manini, Todd M. ;
Nevitt, Michael ;
Newman, Anne B. ;
Goodpaster, Bret H. .
AMERICAN JOURNAL OF CLINICAL NUTRITION, 2009, 90 (06) :1579-1585
1234