Epstein-Barr Virus-Positive T/NK-Cell Lymphoproliferative Diseases in Chinese Mainland

被引：7
作者：
Ai, Junhong [1 ]
Xie, Zhengde [1 ]
机构：
[1] Capital Med Univ, Beijing Childrens Hosp,Natl Clin Res Ctr Resp Dis, Beijing Key Lab Pediat Resp Infect Dis,Minist Edu, Key Lab Major Dis Children,Beijing Pediat Res Ins, Beijing, Peoples R China
来源：
FRONTIERS IN PEDIATRICS | 2018年 / 6卷
基金：
北京市自然科学基金;
关键词：
Epstein-Barr virus; T/natural killer cell; lymphoproliferative disorder; clinical feature; China; VACCINIFORME-LIKE LYMPHOMA;
D O I：
10.3389/fped.2018.00289
中图分类号：
R72 [儿科学];
学科分类号：
100202 ;
摘要：
Epstein-Barr virus-positive T/NK-cell lymphoproliferative disorders (EBV + T/NK LPD) encompass a heterogeneous group of disorders, including chronic active Epstein-Barr virus infection (CAEBV), Epstein-Barr virus-associated hemophagocytic lymphohistiocytosis (EBV-HLH), systemic EBV + T-cell lymphoma of childhood and hydroa vacciniforme-like lymphoproliferative disorder (HVLPD) and so on, predominantly affecting children and young adults with high mortality. Patients with EBV + T/NK LPD have overlapping clinical symptoms as well as histologic and immunophenotypic features. In this review, we summarized the clinical features of EBV + T/NK LPD in Chinese patients from the published articles.
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页数：5
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