Shaping Dendritic Spines in Autism Spectrum Disorder: mTORC1-Dependent Macroautophagy

被引:24
作者
Bowling, Heather [1 ]
Klann, Eric [1 ]
机构
[1] NYU, Ctr Neural Sci, New York, NY 10003 USA
关键词
SIGNALING PATHWAYS; MICE; TRANSLATION; MODEL; MTOR;
D O I
10.1016/j.neuron.2014.08.021
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
In this issue of Neuron, Tang et al. (2014) explore the relationship between developmental dendritic pruning, elevated mTORC1 signaling, macroautophagy, and autism spectrum disorder. The study provides valuable new insight into mTORC1-dependent cellular dysfunction and neurodevelopmental disorders.
引用
收藏
页码:994 / 996
页数:3
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