Donor leukocyte infusion after allogeneic bone marrow transplantation was not effective for relapsed rhabdomyosarcoma

被引：5

作者：

Moritake, H

Ikuno, Y

Tasaka, H

Koga, H

Miyazaki, S

Okamura, J

机构：

[1] Kyushu Natl Canc Ctr, Sect Pediat, Minami Ku, Fukuoka 815, Japan

[2] Saga Med Coll, Dept Pediat, Saga, Japan

来源：

BONE MARROW TRANSPLANTATION | 1998年 / 21卷 / 07期

关键词：

rhabdomyosarcoma; alloBMT; DLI;

D O I：

10.1038/sj.bmt.1701150

中图分类号：

Q6 [生物物理学];

学科分类号：

071011 ;

摘要：

A 10-year-old boy with metastatic rhabdomyosarcoma had an HLA-identical sibling and received an allogeneic BMT. Recurrence was detected in the BM as the only site of treatment failure 12 months after BMT. Donor leukocyte infusion (DLI) was chosen as salvage therapy. Although sufficient cells (a total of 29.7 x 10(7)/kg) were infused, no signs of acute GVHD nor Bill aplasia occurred and the patient died of disease progression 9 months after DLI.

引用

页码：725 / 726

页数：2

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