Controversies in the therapy of isolated congenital complete heart block

被引:5
作者
Dolara, Alberto [1 ]
Favilli, Silvia [2 ]
机构
[1] Univ A Meyer, Agenzia Reg Sanita, Florence, Italy
[2] Univ A Meyer, UO Cardiol Pediatr, Azienda Osped, Florence, Italy
关键词
anti-Ro antibodies; cardiomyopathy; congenital complete heart block; pacemaker; COMPLETE ATRIOVENTRICULAR-BLOCK; FETAL TREATMENT IMPROVES; DIAGNOSED IN-UTERO; NATURAL-HISTORY; VENTRICULAR-FUNCTION; PR INTERVAL; CHILDREN; DEXAMETHASONE; TERBUTALINE; RISK;
D O I
10.2459/JCM.0b013e3283397801
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Controversies in the therapy of congenital complete heart block are reviewed in terms of the timing of pacemaker implantation, the type and complications of pacing and its role in the presence of myocardial dysfunction. Drug treatment may be useful in selected cases in the presence of pleural effusions, ascites and hydrops of the fetus, but have no effect on complete heart block. Administration of fluorinated steroids in anti-Ro antibody-positive mothers with the aim of preventing complete heart block has given controversial results. Because of the variety of the clinical presentations, especially in regard to pacing therapy, it is mandatory to refer patients with congenital complete heart block to specialized centers with adequate resources and experienced personnel. J Cardiovasc Med 11:426-430 (C) 2010 Italian Federation of Cardiology.
引用
收藏
页码:426 / 430
页数:5
相关论文
共 74 条
[71]   Presentation and prognosis of complete atrioventricular block in childhood, according to maternal antibody status [J].
Villain, Elisabeth ;
Coastedoat-Chalumeau, Nathalie ;
Marijon, Eloi ;
Boudjemline, Younes ;
Piette, Jean-Charles ;
Bonnet, Damien .
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2006, 48 (08) :1682-1687
[72]   Specificity and effector mechanisms of autoantibodies in congenital heart block [J].
Wahren-Herlenius, Marie ;
Sonesson, Sven-Erik .
CURRENT OPINION IN IMMUNOLOGY, 2006, 18 (06) :690-696
[73]   Treatment of fetal congenital complete heart block with maternal administration of beta-sympathomimetics (terbutaline) - A case report [J].
Yoshida, H ;
Iwamoto, M ;
Sakakibara, H ;
Shigeta, H ;
Hirahara, F ;
Sato, K .
GYNECOLOGIC AND OBSTETRIC INVESTIGATION, 2001, 52 (02) :142-144
[74]   Cardiac adverse effects of early dexamethasone treatment in preterm infants: A randomized clinical trial [J].
Zecca, E ;
Papacci, P ;
Maggio, L ;
Gallini, F ;
Elia, S ;
De Rosa, G ;
Romagnoli, C .
JOURNAL OF CLINICAL PHARMACOLOGY, 2001, 41 (10) :1075-1081