The Role of 18F-FDG PET/CT in Suspected Intraocular Sarcoidosis and Tuberculosis

被引：15
作者：
Burger, C. [1 ,2 ]
Holness, J. L. [1 ,2 ]
Smit, D. P. [2 ,3 ]
Griffith-Richards, S. [2 ,4 ]
Koegelenberg, C. F. N. [2 ,5 ]
Ellmann, A. [1 ,2 ]
机构：
[1] Tygerberg Hosp, Div Nucl Med, Francie van Zijl Dr, ZA-7505 Cape Town, South Africa
[2] Stellenbosch Univ, Francie van Zijl Dr, ZA-7505 Cape Town, South Africa
[3] Tygerberg Hosp, Ophthalmol, Cape Town, South Africa
[4] Tygerberg Hosp, Radiodiag, Cape Town, South Africa
[5] Tygerberg Hosp, Pulmonol, Cape Town, South Africa
来源：
OCULAR IMMUNOLOGY AND INFLAMMATION | 2021年 / 29卷 / 03期
关键词：
Uveitis; tuberculosis; sarcoidosis; PET; CT; imaging; POSITRON-EMISSION-TOMOGRAPHY; COMPUTERIZED-TOMOGRAPHY; OCULAR TUBERCULOSIS; UVEITIS; CHEST; DIAGNOSIS; PATTERNS;
D O I：
10.1080/09273948.2019.1685109
中图分类号：
R77 [眼科学];
学科分类号：
100212 ;
摘要：
Purpose: To determine the utility of fluorine-18 fluorodeoxyglucose Positron Emission Tomography Computed Tomography (FDG PET/CT) in patients with suspected ocular sarcoidosis (OS) or intraocular tuberculosis (IOTB) in a resource-constrained, TB endemic area. Methods: Independent review of the FDG PET/CTs, Computed Tomography (CT) scans and chest radiographs (CXRs) of patients with suspected OS or IOTB and inconclusive conventional workup. Results: Twenty-nine PET/CTs and CXRs were reviewed, with 38% of PET/CTs and CTs demonstrating evidence of TB or sarcoidosis, compared to 21% of CXRs. The sensitivity, specificity, positive and negative predictive values for PET/CT and CT were similar - 85.7%, 95.5%, 85.7% and 95.5% for OS, and 33.3%, 100%, 100% and 68% for IOTB respectively and for CXR, 57.1%, 100%, 100% and 88% for OS, and 16.7%, 100%, 100% and 63% for IOTB. Conclusion: PET/CT added no significant additional benefit over Chest CT in patients with suspected OS or IOTB.
引用
收藏
页码：530 / 536
页数：7
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