The relationship between metabolic syndrome and obstructive sleep apnea syndrome: a nationwide population-based study

被引:43
作者
Kim, Do Hyun [1 ]
Kim, Bongseong [2 ]
Han, Kyungdo [2 ]
Kim, Soo Whan [1 ]
机构
[1] Catholic Univ Korea, Seoul St Marys Hosp, Dept Otolaryngol Head & Neck Surg, Coll Med, Banpo Daero 222, Seoul 137701, South Korea
[2] Soongsil Univ, Dept Stat & Actuarial Sci, 369 Sangdo Ro, Seoul 06978, South Korea
关键词
GLUCOSE-INTOLERANCE; INSULIN-RESISTANCE; ADIPOSE-TISSUE; RISK-FACTORS; OBESITY; ASSOCIATION; HEALTH; EPIDEMIOLOGY; DEFINITION; PREVALENCE;
D O I
10.1038/s41598-021-88233-4
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
There has been a need for research on the association between metabolic syndrome (MetS) and obstructive sleep apnea syndrome (OSAS) using large data such as nationwide population-based data that adjusts important confounding factors. Therefore, we investigated the relationship between MetS and OSAS. The data source we used was the National Health Insurance Service claims database managed by the Republic of Korea government, in which 10,113,560 individuals were enrolled in 2009 and followed up until 2018. The independent association of MetS with the risk of OSAS was determined using a Cox proportional hazards model with adjustment for age, sex, smoking status, alcohol consumption, regular physical exercise, and body mass index. Our results showed that MetS were strongly associated to OSAS which was adjusted for several confounding factors. Also, we found men, increased waist circumference and increased triglyceride are important risk factors for OSAS.
引用
收藏
页数:8
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