Determination of semivolatile organic compounds in exhaled breath condensate by gas chromatography-mass spectrometry

被引：4
|
作者：
Rodionov, A. A. [1 ]
Revelsky, A. I. [1 ]
Revelsky, I. A. [1 ]
Anokhina, T. N. [2 ]
Anaev, E. Kh. [2 ]
机构：
[1] Moscow MV Lomonosov State Univ, Dept Chem, Moscow 119991, Russia
[2] Med Univ, Fed Res Inst Pulmonol, Moscow 105077, Russia
来源：
JOURNAL OF ANALYTICAL CHEMISTRY | 2014年 / 69卷 / 14期
关键词：
exhaled breath condensate; GC-MS; extraction; adsorption preconcentration; COLLECTION; ALDEHYDES;
D O I：
10.1134/S1061934814140081
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
A method is proposed for determining semivolatile organic compounds in exhaled breath condensate by gas chromatography-mass spectrometry (GC-MS) with preliminary liquid-liquid extraction and adsorption preconcentration of analytes from the extract obtained. The introduction of a significant portion of the resulting preconcentrate (up to 100 mu L) into the chromatograph injector substantially lowered the detection limits for analytes. The experiment revealed a number of substances that have not been previously identified in the exhaled breath condensate. A list of these compounds is presented in the article.
引用
收藏
页码：1330 / 1336
页数：7
相关论文
共 50 条
  • [1] Determination of semivolatile organic compounds in exhaled breath condensate by gas chromatography-mass spectrometry
    A. A. Rodionov
    A. I. Revelsky
    I. A. Revelsky
    T. N. Anokhina
    E. Kh. Anaev
    Journal of Analytical Chemistry, 2014, 69 : 1330 - 1336
  • [2] Metabolomics Study of Exhaled Breath Condensate in Childhood Asthma by Gas Chromatography-Mass Spectrometry
    Jiang Ming-Chen
    Wang Shou-Chuan
    Xu Shan
    Xu Qiu-Yue
    Shan Jin-Jun
    Xie Tong
    Peng Lin-Xiu
    Dai Qi-Gang
    CHINESE JOURNAL OF ANALYTICAL CHEMISTRY, 2018, 46 (06) : 969 - 974
  • [3] Development of a method for metabolomic analysis of human exhaled breath condensate by gas chromatography-mass spectrometry in high resolution mode
    Peralbo-Molina, A.
    Calderon-Santiago, M.
    Priego-Capote, F.
    Jurado-Gamez, B.
    Luque de Castro, M. D.
    ANALYTICA CHIMICA ACTA, 2015, 887 : 118 - 126
  • [4] Lyophilization with Subsequent Derivatization vs Microextraction by Packed Sorbent (MEPS) in the Analysis of Exhaled Breath Condensate by Gas Chromatography-Mass Spectrometry
    Revelsky, A., I
    Kozyr, A. S.
    Samokhin, A. S.
    Anaev, E. Kh
    Revelsky, I. A.
    JOURNAL OF ANALYTICAL CHEMISTRY, 2022, 77 (10) : 1294 - 1299
  • [5] Simultaneous Determination of Semivolatile Organic Compounds in Air by Ionic Iiquid-Automatic Thermal Desorber. Gas Chromatography-Mass Spectrometry
    Huo Jiang-Bo
    Wang Xiao-Yi
    Sun Dong-Ling
    Zhao Jing-Qiang
    Lin Xing-Tao
    CHINESE JOURNAL OF ANALYTICAL CHEMISTRY, 2014, 42 (04) : 531 - 535
  • [6] Determination of carbonyl compounds in exhaled breath by on-sorbent derivatization coupled with thermal desorption and gas chromatography-tandem mass spectrometry
    Lomonaco, T.
    Romani, A.
    Ghimenti, S.
    Biagini, D.
    Bellagambi, F. G.
    Onor, M.
    Salvo, P.
    Fuoco, R.
    Di Francesco, F.
    JOURNAL OF BREATH RESEARCH, 2018, 12 (04)
  • [7] Determination of two mouldy compounds in cork by gas chromatography-mass spectrometry
    Tang Xi
    Liang Ming
    Li Xiaojing
    Xiong Wenming
    Tang Hong
    Jiang Xiaoli
    Chen Jiamin
    CHINESE JOURNAL OF CHROMATOGRAPHY, 2012, 30 (07) : 733 - 737
  • [8] Determination of Verapamil in Exhaled Breath Condensate by using Microextraction and Liquid Chromatography
    Pourkarim, Fariba
    Shayanfar, Ali
    Khoubnasabjafari, Maryam
    Akbarzadeh, Fariborz
    Sajedi-Amin, Sanaz
    Jouyban-Gharamaleki, Vahid
    Jouyban, Abolghasem
    CURRENT PHARMACEUTICAL ANALYSIS, 2019, 15 (05) : 535 - 541
  • [9] SIMULTANEOUS DETERMINATION OF ORGANOTIN COMPOUNDS IN WHITE WINE BY GAS CHROMATOGRAPHY-MASS SPECTROMETRY
    Wan, Yi-Qun
    Ma, Ya-Qian
    Mao, Xue-Jin
    ANALYTICAL LETTERS, 2012, 45 (13) : 1799 - 1809
  • [10] Comparison between the Results of the Gas Chromatography-Mass Spectrometry Analysis of Solutions of the Silyl Derivatives of Dried Exhaled Breath Condensate Samples from Patients with Bronchial Asthma and COPD and Healthy Volunteers
    Revel'skii, A., I
    Samokhin, A. S.
    Anaev, E. Kh
    JOURNAL OF ANALYTICAL CHEMISTRY, 2022, 77 (12) : 1553 - 1560
12345