Dosimetric comparison of complete block in ovarian protection between helical tomotherapy and volumetric-modulated arc therapy for cervical cancer

被引:1
作者
Liu, Xianfeng [1 ,2 ]
Wu, Furong [2 ]
Jin, Fu [1 ,2 ]
Sun, Fu [3 ]
Li, Qicheng [2 ]
Guo, Mingfang [4 ]
Zhao, Xiujuan [4 ]
Guo, Qishuai [1 ,2 ]
机构
[1] Chongqing Univ, Chongqing Key Lab Translat Res Canc Metastasis &, Canc Hosp, Chongqing 400030, Peoples R China
[2] Chongqing Univ, Dept Radiat Oncol, Canc Hosp, Chongqing 400044, Peoples R China
[3] Second Peoples Hosp Jiangjin Dist, Dept Oncol, Chongqing 402289, Peoples R China
[4] Chongqing Univ, Dept Gynecol Oncol, Canc Hosp, Chongqing 400044, Peoples R China
关键词
Helical tomotherapy; Volumetric-modulated arc therapy; Dosimetry; gamma passing rate; Ovarian protection; RADIOTHERAPY; IMRT; IRRADIATION; TRANSPOSITION;
D O I
10.1016/j.jrras.2022.01.007
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
This study is aimed at comparing the dosimetric differences of restricting beamlets passing in protecting ovaries between helical tomotherapy (HT) and volumetric-modulated arc therapy (VMAT) for patients with cervical cancer, and particularly comparing the y passing rates of ovaries between the two techniques by independent dose calculations. 15 patients with cervical cancer who had undergone ovarian transposition were randomly enrolled. The HT and VMAT plans were created for each involved patient. Target quality, organs at risk (OARs) sparing, and gamma passing rates of ovaries were compared between HT and VMAT. HT achieved better than VMAT in D-98%, D-2%, D-me(an), conformal index and homogeneity index (P < 0.05). Almost all OARs in HT had lower radiation dose than those in VMAT (P < 0.05). All the gamma passing rates of the ovaries were 100% for the 15 patients both in HT and VMAT. The results suggests that HT outperforms VMAT in terms of target coverage and OARs sparing. Although the calculated dose to the ovaries was accurate both in HT and VMAT, HT showed further advantages for cervical cancer patients with ovarian protection requirements.
引用
收藏
页码:11 / 16
页数:6
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