Highly enantioselective hydrogenation of itaconic acid derivatives with a chiral bisphospholane-Rh(I) catalyst

被引：28

作者：

Almena, J

Monsees, A

Kadyrova, R

Riermeier, TH

Gotov, B

Holz, J

Börner, A

机构：

[1] Degussa AG, Degussa Homogeneous Catalysts, D-63457 Hanau, Germany

[2] Degussa AG, Project House Catalysts, D-65926 Frankfurt, Germany

[3] Univ Rostock EV, Leibniz Inst Organ Katalyse, D-18055 Rostock, Germany

[4] Univ Rostock, Fachbereich Chem, D-18059 Rostock, Germany

来源：

ADVANCED SYNTHESIS & CATALYSIS | 2004年 / 346卷 / 11期

关键词：

asymmetric catalysis; chiral bisphospholanes; enantioselective hydrogenation; homogeneous catalysis; P ligands; rhodium;

D O I：

10.1002/adsc.200404080

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

The new - commercially in multi-kg quantities available - chiral bisphospholane ligand, catA-Sium(R) M, has been successfully used in the Rh(I)catalysed enantioselective hydrogenation of itaconic acid derivatives. Chiral beta-substituted succinic acid derivatives were produced in good to excellent enantioselectivities. Turnover frequencies by up to 40,000 h(-1) have been achieved.

引用

页码：1263 / 1266

页数：4

共 27 条

[1]

BLAER HU, 2003, ASYMMETRIC CATALYSIS

[2] Enantioselective catalysis in fine chemicals production [J].