Controversies about the use of serological markers in diagnosis of inflammatory bowel disease

被引:5
作者
Xie, Qin [2 ]
Gan, Hua-Tian [1 ]
机构
[1] Sichuan Univ, Dept Geriatr, W China Hosp, Chengdu 610041, Sichuan, Peoples R China
[2] Sichuan Univ, Dept Gastroenterol, W China Hosp, Chengdu 610041, Sichuan, Peoples R China
关键词
Inflammatory bowel diseases; D-lactate; Diamine oxidase; Intestinal permeability; Diagnosis; INCREASED INTESTINAL PERMEABILITY; D-LACTATE; CROHNS-DISEASE; DIAMINE OXIDASE; METABOLISM; RELATIVES;
D O I
10.3748/wjg.v16.i2.279
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
The serological markers are increasingly used in diagnosis of inflammatory bowel disease (IBD). D-lactate and diamine oxidase are new indicators that can be used to reveal the damage to intestinal mucosa and permeability alteration in IBD. Although the two biological markers seem more sensitive, recent clinical trials and animal experiments have shown controversies about the use of them in diagnosis of IBD. Therefore, these markers should be interpreted cautiously and further prospective studies are needed to establish their clinical role in diagnosis of IBD. (C) 2010 Baishideng. All rights reserved.
引用
收藏
页码:279 / 280
页数:2
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