Hepatitis B and C among patients with hidradenitis suppurativa: a population-based study

被引：3

作者：

Cohen, Jeffrey M. ^{[1
]}

Kridin, Khalaf ^{[2
]}

Perez-Chada, Lourdes M. ^{[3
]}

Merola, Joseph F. ^{[3
,4
]}

Cohen, Arnon D. ^{[5
,6
]}

机构：

[1] Yale Sch Med, Dept Dermatol, New Haven, CT USA

[2] Rambam Hlth Campus, Dept Dermatol, Haifa, Israel

[3] Harvard Med Sch, Dept Dermatol, Brigham & Womens Hosp, Boston, MA 02115 USA

[4] Harvard Med Sch, Brigham & Womens Hosp, Dept Med, Divs Rheumatol, Boston, MA 02115 USA

[5] Clalit Hlth Serv, Dept Qual Measures & Res, Chief Phys Off, Tel Aviv, Israel

[6] Ben Gurion Univ Negev, Fac Hlth Sci, Siaal Res Ctr Family Med & Primary Care, Beer Sheva, Israel

来源：

INTERNATIONAL JOURNAL OF DERMATOLOGY | 2022年 / 61卷 / 01期

关键词：

INCREASED TH17 CELLS; VIRUS; PSORIASIS; PATHOGENESIS; CONTRIBUTE;

D O I：

10.1111/ijd.15578

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Background Hidradenitis suppurative (HS) is a chronic inflammatory condition related to multiple systemic diseases and infections. Methods This retrospective cross-sectional study from 1999 to 2015 used the database of Clalit Health Services, the largest managed care organization in Israel, to explore the association between HS and hepatitis B and C. Sociodemographic and clinical information was compared using chi(2) tests for sex and socioeconomic status and t-tests for age. Logistic regression was used to calculate odds ratios (ORs) and 95% confidence intervals (CIs) to compare the odds of hepatitis B and C in those with and without HS. Results In multivariate analysis controlling for sex, age as a continuous variable, Arab ancestry, and history of drug abuse, HS was associated with a 1.87-fold increased odds (95% CI 1.11-3.17, P = 0.019) of hepatitis B (HBV). HS was also associated with HCV in multivariate analysis controlling for sex, age per year, Arab ancestry, alcohol use, and drug use, with a 1.74-fold increased odds (95% CI 1.05-2.89, P = 0.032) of hepatitis C (HCV) among those with HS as compared to controls. Conclusions This study demonstrated an association between HS and both hepatitis B and hepatitis C.

引用

页码：84 / 88

页数：5