Jointly interventional and observational data: estimation of interventional Markov equivalence classes of directed acyclic graphs

被引:49
作者
Hauser, Alain [1 ,2 ]
Buehlmann, Peter [3 ]
机构
[1] Univ Bern, CH-3012 Bern, Switzerland
[2] Swiss Inst Bioinformat, Lausanne, Switzerland
[3] ETH, Zurich, Switzerland
关键词
Bayesian information criterion; Causal inference; Graphical model; Greedy equivalence search; Interventions; Maximum likelihood estimation; CAUSAL; MODEL; NETWORKS;
D O I
10.1111/rssb.12071
中图分类号
O21 [概率论与数理统计]; C8 [统计学];
学科分类号
020208 ; 070103 ; 0714 ;
摘要
In many applications we have both observational and (randomized) interventional data. We propose a Gaussian likelihood framework for joint modelling of such different data types, based on global parameters consisting of a directed acyclic graph and corresponding edge weights and error variances. Thanks to the global nature of the parameters, maximum likelihood estimation is reasonable with only one or few data points per intervention. We prove consistency of the Bayesian information criterion for estimating the interventional Markov equivalence class of directed acyclic graphs which is smaller than the observational analogue owing to increased partial identifiability from interventional data. Such an improvement in identifiability has immediate implications for tighter bounds for inferring causal effects. Besides methodology and theoretical derivations, we present empirical results from real and simulated data.
引用
收藏
页码:291 / 318
页数:28
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