Programming DNA replication origins and chromosome organization

被引：43
作者：
Cayrou, Christelle [1 ]
Coulombe, Philippe [1 ]
Mechali, Marcel [1 ]
机构：
[1] CNRS, Inst Human Genet, F-34980 Montpellier, France
来源：
CHROMOSOME RESEARCH | 2010年 / 18卷 / 01期
基金：
欧洲研究理事会;
关键词：
DNA replication origin; Chromatin; Nucleosome; DNA Loops; Transcription; Mitosis; Reprogramming; MATRIX ATTACHMENT REGIONS; HISTONE ACETYLTRANSFERASE HBO1; NUCLEAR-MATRIX; GENOME-WIDE; SCHIZOSACCHAROMYCES-POMBE; REPLICON CLUSTERS; INITIATION SITES; MAMMALIAN-CELLS; CHROMATIN LOOP; TRANSCRIPTION;
D O I：
10.1007/s10577-009-9105-3
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
During each cell cycle, thousands of DNA replication origins are activated in each cell of a metazoan organism. Although they appear site-specific, their usage and organization are rather plastic. Moreover, no strict sequence specificity has been observed in contrast to bacterial or Saccharomyces cerevisiae DNA replication origins. Epigenetic regulation linked to chromatin structure, chromosome organization, and transcription has been suggested to explain how DNA replication origins are selected and recognized by replication initiation factors. In this paper, we review these epigenetic features and discuss how, during the previous mitosis, chromosomal architecture might prepare DNA replication origins for a new cell cycle.
引用
收藏
页码：137 / 145
页数：9
相关论文
共 78 条
  • [71] Sequence-independent DNA binding and replication initiation by the human origin recognition complex
    Vashee, S
    Cvetic, C
    Lu, WY
    Simancek, P
    Kelly, TJ
    Walter, JC
    [J]. GENES & DEVELOPMENT, 2003, 17 (15) : 1894 - 1908
  • [72] ATP-dependent chromatin remodeling shapes the DNA replication landscape
    Vincent, Jack A.
    Kwong, Tracey J.
    Tsukiyama, Toshio
    [J]. NATURE STRUCTURAL & MOLECULAR BIOLOGY, 2008, 15 (05) : 477 - 484
  • [73] Histone acetylation regulates the time of replication origin firing
    Vogelauer, M
    Rubbi, L
    Lucas, I
    Brewer, BJ
    Grunstein, M
    [J]. MOLECULAR CELL, 2002, 10 (05) : 1223 - 1233
  • [74] SUPERCOILED LOOPS AND EUKARYOTIC DNA-REPLICATION
    VOGELSTEIN, B
    PARDOLL, DM
    COFFEY, DS
    [J]. CELL, 1980, 22 (01) : 79 - 85
  • [75] A distinct G(1) step required to specify the Chinese hamster DHFR replication origin
    Wu, JR
    Gilbert, DM
    [J]. SCIENCE, 1996, 271 (5253) : 1270 - 1272
  • [76] Role for Plk1 phosphorylation of Hbo1 in regulation of replication licensing
    Wu, Zhao-Qiu
    Liu, Xiaoqi
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2008, 105 (06) : 1919 - 1924
  • [77] Genome-scale identification of nucleosome positions in S-cerevisiae
    Yuan, GC
    Liu, YJ
    Dion, MF
    Slack, MD
    Wu, LF
    Altschuler, SJ
    Rando, OJ
    [J]. SCIENCE, 2005, 309 (5734) : 626 - 630
  • [78] Cell cycle regulation of chromatin at an origin of DNA replication
    Zhou, J
    Chau, CM
    Deng, Z
    Shiekhattar, R
    Spindler, MP
    Schepers, A
    Lieberman, PM
    [J]. EMBO JOURNAL, 2005, 24 (07) : 1406 - 1417
12345678