Objective-To describe the surgical technique, early results and complications of tibial tuberosity advancement (TTA) for treatment for cranial cruciate ligament (CrCL)-deficient stifle joints in dogs. Study Design-Retrospective clinical study. Animals-Dogs (n = 101) with CrCL-deficient stifles (114). Methods-Medical records of 10 1 dogs that had TTA were reviewed. Complications were recorded and separated into either major or minor complications based on the need for additional surgery. In-hospital re-evaluation of limb function and time to radiographic healing were reviewed. Further follow-up was obtained by telephone interview of owners. Results-Complications occurred in 31.5% of the dogs (12.3% major, 19.3% minor). Major complications included subsequent meniscal tear, tibial fracture, implant failure, infection, lick granuloma, incisional trauma, and medial patellar luxation; all major complications were treated with successful outcomes. All but 2 minor complications resolved. The mean time to documented radiographic healing was 11.3 weeks. Final in-hospital re-evaluation of limb function (mean, 13.5 weeks), was recorded for 93 dogs with lameness categorized as none (74.5%), mild (23.5%), moderate (2%), and severe (1%). All but 2 owners interviewed were satisfied with outcome and 83.1 % reported a marked improvement or a return to pre-injury status. Conclusions-TTA is a procedure comparable with alternate methods of CrCL repair with expected good to excellent functional outcome. Clinical Relevance-TTA procedure can be successfully used to obtain the dynamic stability of a CrCL-deficient stifle joint in dogs. (c) Copyright 2007 by The American College of Veterinary Surgeons.