High burden of RSV hospitalization in very young children: a data linkage study

被引：57

作者：

Homaira, N. ^{[1
]}

Oei, J. -L. ^{[1
,2
]}

Mallitt, K-A. ^{[1
]}

Abdel-Latif, M. E. ^{[3
]}

Hilder, L. ^{[4
,5
]}

Bajuk, B. ^{[6
]}

Lui, K. ^{[1
]}

Ferson, M. ^{[7
,8
]}

Nurkic, A. ^{[7
]}

Chambers, G. M. ^{[4
,5
]}

Rawlinson, W. ^{[9
,10
,11
]}

Snelling, T. ^{[12
,13
,14
,15
]}

Jaffe, A. ^{[1
,16
]}

机构：

[1] UNSW Australia, Discipline Paediat, Sch Womens & Childrens Hlth, Fac Med, Randwick, NSW 2031, Australia

[2] Royal Hosp Women, Dept Newborn Care, Sydney, NSW, Australia

[3] Australian Natl Univ, Centenary Hosp, Dept Neonatol, Canberra, ACT 0200, Australia

[4] UNSW Australia, Natl Perinatal Epidemiol & Stat Unit, Ctr Big Data Res Hlth, Randwick, NSW 2031, Australia

[5] UNSW Australia, Sch Womens & Childrens Hlth, Randwick, NSW 2031, Australia

[6] Sydney Childrens Hosp Network, NSW Pregnancy & Newborn Serv Network, Westmead, NSW, Australia

[7] South Eastern Sydney Local Hlth Dist, Publ Hlth Unit, Sydney, NSW, Australia

[8] UNSW Australia, Fac Med, Sch Publ Hlth & Community Med, Randwick, NSW 2031, Australia

[9] Prince Wales Hosp, SEALS Microbiol, Serol & Virol Div, Randwick, NSW 2031, Australia

[10] UNSW Australia, Sch Med Sci, Randwick, NSW 2031, Australia

[11] UNSW Australia, Sch Biotechnol & Bimol Sci, Randwick, NSW 2031, Australia

[12] Princess Margaret Hosp, Perth, WA, Australia

[13] Univ Western Australia, Telethon Kids Inst, Wesfarmers Ctr Vaccines & Infect Dis, Nedlands, WA 6009, Australia

[14] Menzies Sch Hlth Res, Darwin, NT, Australia

[15] Charles Darwin Univ, Darwin, NT 0909, Australia

[16] Sydney Childrens Hosp, Resp Dept, Sydney, NSW, Australia

来源：

EPIDEMIOLOGY AND INFECTION | 2016年 / 144卷 / 08期

关键词：

Epidemiology; estimating disease prevalence; global vaccine issues; infectious disease epidemiology; paediatrics; RESPIRATORY SYNCYTIAL VIRUS; ALASKA NATIVE INFANTS; TRACT INFECTIONS; DISEASE; BRONCHIOLITIS; SURVEILLANCE; INFLUENZA; GS-5806; HEALTH; ASTHMA;

D O I：

10.1017/S0950268815003015

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

Linked administrative population data were used to estimate the burden of childhood respiratory syncytial virus (RSV) hospitalization in an Australian cohort aged <5 years. RSV-coded hospitalizations data were extracted for all children aged <5 years born in New South Wales (NSW), Australia between 2001 and 2010. Incidence was calculated as the total number of new episodes of RSV hospitalization divided by the child-years at risk. Mean cost per episode of RSV hospitalization was estimated using public hospital cost weights. The cohort comprised of 870 314 children. The population-based incidence/1000 child-years of RSV hospitalization for children aged <5 years was 4.9 with a rate of 25.6 in children aged <3 months. The incidence of RSV hospitalization (per 1000 child-years) was 11.0 for Indigenous children, 81.5 for children with bronchopulmonary dysplasia (BPD), 10.2 for preterm children with gestational age (GA) 32-36 weeks, 27.0 for children with GA 28-31 weeks, 39.0 for children with GA <28 weeks and 6.7 for term children with low birthweight. RSV hospitalization was associated with an average annual cost of more than AUD 9 million in NSW. RSV was associated with a substantial burden of childhood hospitalization specifically in children aged <3 months and in Indigenous children and children born preterm or with BPD.

引用

页码：1612 / 1621

页数：10

共 39 条

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