Chitosan-silica Sulfate Nano Hybrid: An Efficient Biopolymer Based-heterogeneous Nano Catalyst for Solvent-free Synthesis of 3,4-Dihydropyrimidine-2 (1H) -one/thiones

被引：5

作者：

Behrouz, Somayeh ^{[1
]}

Abi, Masoome Nazar ^{[1
]}

Piltan, Mohammad Amin ^{[1
]}

机构：

[1] Shiraz Univ Technol, Dept Chem, Med Chem Res Lab, Shiraz 71555313, Iran

来源：

ACTA CHIMICA SLOVENICA | 2021年 / 68卷 / 02期

关键词：

Chitosan-silica sulfate nano hybrid; 3,4-Dihydropyrimidines; green chemistry; heterogeneous catalysis; multicomponent reaction; ONE-POT SYNTHESIS; HIGHLY EFFICIENT; 3-COMPONENT SYNTHESIS; BIGINELLI REACTION; GREEN SYNTHESIS; GRAPHENE OXIDE; SULFURIC-ACID; NANOCATALYST; DERIVATIVES; PROFICIENT;

D O I：

10.17344/acsi.2020.6343

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A green and highly efficient approach for the synthesis of 3,4-dihydropyrimidine-2(1H)-one/thione derivatives is described. In this approach, the three-component Biginelli reaction between (thio)urea, methyl acetoacetate and aldehydes under solvent-free condition in the presence of chitosan-silica sulfate nano hybrid (CSSNH) as a green and heterogeneous nano catalyst affords the corresponding products in good to excellent yields and in short reaction times. CSSNH is a cheap, eco-friendly, and non-toxic nano catalyst that could be easily prepared, handled, and reused for many reaction runs without significant loss of its activity.

引用

页码：374 / 386

页数：13

共 50 条

[11] Chitosan-Silica Sulfate Nano Hybrid as a Novel and Highly Proficient Heterogeneous Nano Catalyst for Regioselective Ring Opening of Epoxides via Carboxylic Acids [J].

Behrouz, Somayeh ;

Rad, Mohammad Navid Soltani ;

Piltan, Mohammad Amin ;

Doroodmand, Mohammad Mahdi .

HELVETICA CHIMICA ACTA, 2017, 100 (09)

[12] Highly Efficient One-Pot Three Component Synthesis of 2H-Indazoles by Consecutive Condensation, C-N and N-N Bond Formations Using Cu/Aminoclay/Reduced Graphene Oxide Nanohybrid [J].

Behrouz, Somayeh .

JOURNAL OF HETEROCYCLIC CHEMISTRY, 2017, 54 (03) :1863-1871

[13] Highly efficient three-component synthesis of 5-substituted-1H-tetrazoles from aldehydes, hydroxylamine, and tetrabutylammonium azide using doped nano-sized copper(I) oxide (Cu2O) on melamine-formaldehyde resin [J].

Behrouz, Somayeh .

JOURNAL OF SAUDI CHEMICAL SOCIETY, 2017, 21 (02) :220-228

[14]

Belferdi F., ACTA CHIM SLOV, V2021

[15]

Biginelli P., 1893, GAZZ CHIM ITAL, V23, P360

[16] A mini-review on Biginelli adducts with notable pharmacological properties [J].

de Fatima, Angelo ;

Braga, Taniris C. ;

Neto, Leonardo da S. ;

Terra, Bruna S. ;

Oliveira, Breno G. F. ;

da Silva, Daniel L. ;

Modolo, Luzia V. .

JOURNAL OF ADVANCED RESEARCH, 2015, 6 (03) :363-373

[17] 1,3,5-Tris(2-hydroxyethyl)isocyanurate functionalized graphene oxide: a novel and efficient nanocatalyst for the one -pot synthesis of 3,4-dihydropyrimidin-2(1H)-ones [J].

Dekamin, Mohammad G. ;

Mehdipoor, Fatemeh ;

Yaghoubi, Amene .

NEW JOURNAL OF CHEMISTRY, 2017, 41 (14) :6893-6901

[18] Chemistry and Biology Of Multicomponent Reactions [J].

Domling, Alexander ;

Wang, Wei ;

Wang, Kan .

CHEMICAL REVIEWS, 2012, 112 (06) :3083-3135

[19] Experimental and theoretical study on a one-pot, three-component route to 3,4-dihydropyrimidin-2(1H)-ones/thiones TiCl3OTf-[bmim]Cl [J].

Farhadi, Asadollah ;

Noei, Jalil ;

Aliyari, Rasoul Haji ;

Albakhtiyari, Maryam ;

Takassi, Mohammad Ali .

RESEARCH ON CHEMICAL INTERMEDIATES, 2016, 42 (02) :1401-1409

[20] A green synthesis of 3,4-dihydropyrimidine-2(1H)-one/thione derivatives using nanosilica-supported tin(II) chloride as a heterogeneous nanocatalyst [J].

Ghomi, Javad Safaei ;

Teymuri, Raheleh ;

Ziarati, Abolfazl .

MONATSHEFTE FUR CHEMIE, 2013, 144 (12) :1865-1870

← 1 2 3 4 5 →