Snoopy-a unifying Petri net framework to investigate biomolecular networks

被引：82

作者：

Rohr, Christian ^{[1
,2
,3
]}

Marwan, Wolfgang ^{[1
,2
]}

Heiner, Monika ^{[3
]}

机构：

[1] Otto Von Guericke Univ, Magdeburg Ctr Syst Biol MaCS, Magdeburg, Germany

[2] Max Planck Inst Dynam Complex Tech Syst, Magdeburg, Germany

[3] Brandenburg Tech Univ Cottbus, Dept Comp Sci, Cottbus, Germany

来源：

BIOINFORMATICS | 2010年 / 26卷 / 07期

关键词：

D O I：

10.1093/bioinformatics/btq050

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

To investigate biomolecular networks, Snoopy provides a unifying Petri net framework comprising a family of related Petri net classes. Models can be hierarchically structured, allowing for the mastering of larger networks. To move easily between the qualitative, stochastic and continuous modelling paradigms, models can be converted into each other. We get models sharing structure, but specialized by their kinetic information. The analysis and iterative reverse engineering of biomolecular networks is supported by the simultaneous use of several Petri net classes, while the graphical user interface adapts dynamically to the active one. Built-in animation and simulation are complemented by exports to various analysis tools. Snoopy facilitates the addition of new Petri net classes thanks to its generic design.

引用

页码：974 / 975

页数：2