Description of a novel test for the early detection of Alzheimer's disease

被引:20
作者
Cuetos-Vega, F.
Menendez-Gonzalez, M.
Calatayud-Noguera, T.
机构
[1] Univ Oviedo, Fac Psicol, Dept Psicol, E-33003 Oviedo, Asturias, Spain
[2] Hosp Alvarez Buylla Mieres, Neurol Unit, Mieres, Spain
[3] Univ Oviedo, Cent Hosp, Serv Neurol, E-33003 Oviedo, Asturias, Spain
关键词
Alzheimer's disease; early diagnosis test; mild cognitive impairment;
D O I
10.33588/rn.4408.2006403
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Introduction. Diagnosing Alzheimer's disease (AD) as soon as possible is critical to achieve an effective treatment of patients. Aim. To make up a test capable of differentiating those patients suffering,front the early stages of AD compared to healthy people or patients with mild cognitive impairment (MCI). Subjects and methods. A test with 10 memory and language tasks was applied to 85 people: 34 in the early stage of probable AD, 26 with MCI, and 25 healthy people. The groups did not differ with regard to age, sex or studies. Results. The analysis of variance showed significative differences between groups in all tasks as well as in the global score. Sensibility and specificity were calculated to MCI and AD. Conclusions. We designed a new test to detect AD patients on an early stage that is quick and easy to apply. The preliminary scale results in controls, MCI and early AD are shown.
引用
收藏
页码:469 / 474
页数:6
相关论文
共 28 条
  • [1] Alberca R, 1999, Neurologia, V14, P344
  • [2] Boada M, 1999, MED CLIN-BARCELONA, V113, P690
  • [3] Böhm P, 2005, NEUROLOGIA, V20, P402
  • [4] Validation of a model for the prediction of verbal semantic fluency
    Carnero, C
    Maestre, J
    Marta, J
    Mola, S
    Olivares, J
    Sempere, AP
    [J]. REVISTA DE NEUROLOGIA, 2000, 30 (11) : 1012 - 1015
  • [5] The Photo Test
    Carnero-Pardo, C
    Montoro-Ríos, MT
    [J]. REVISTA DE NEUROLOGIA, 2004, 39 (09) : 801 - 806
  • [6] The utility of the semantic verbal fluency test in diagnosis of dementia
    Carnero-Pardo, C
    Lendínez-González, A
    [J]. REVISTA DE NEUROLOGIA, 1999, 29 (08) : 709 - 714
  • [7] Cognitive tests that best discriminate between presymptomatic AD and those who remain nondemented
    Chen, P
    Ratcliff, G
    Belle, SH
    Cauley, JA
    DeKosky, ST
    Ganguli, M
    [J]. NEUROLOGY, 2000, 55 (12) : 1847 - 1853
  • [8] Lexical processing in Spanish patients with probable Alzheimer's disease
    Cuetos, F
    Martinez, T
    Martinez, C
    Izura, C
    Ellis, AW
    [J]. COGNITIVE BRAIN RESEARCH, 2003, 17 (03): : 549 - 561
  • [9] Cuetos F., 2003, Revista espanola de Neuropsicologia, V5, P15
  • [10] Semantic knowledge of famous people in mild cognitive impairment and progression to Alzheimer's disease
    Estévez-González, A
    García-Sánchez, C
    Boltes, A
    Otermín, P
    Pascual-Sedano, B
    Gironell, A
    Kulisevsky, J
    [J]. DEMENTIA AND GERIATRIC COGNITIVE DISORDERS, 2004, 17 (03) : 188 - 195